The effect of fasciculus cuneatus lesions on finger positioning and long-latency reflexes in monkeys.
The effect of fasciculus cuneatus lesions on finger positioning and long-latency reflexes in monkeys.
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楔束损伤对猴子手指定位和长潜伏期反射的影响。
DOI：
10.1007/bf00227785
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发表时间：
1993
影响因子：
2
通讯作者：
Cooper,BY
中科院分区：
文献类型：
--
作者：
Glendinning,DS;VierckJr,CJ;Cooper,BY
先前的研究已经报道了灵长类动物楔束（FC）中断后精细手和手指运动的异常。我们在这里报告说，许多这些赤字可能是由于无法积极调节手指的位置。三只猕猴接受训练，以保持食指在一个位置，以应对恒定或变化的负载。周期性地，扭矩脉冲用于引起手指肌肉的反射。单侧FC损伤后，猴子在试验期间未能调整手指位置，手指肌肉中不存在正常的M2长潜伏期反应。只有在完全病变（包括FC的深腹侧部分）的猴子中，任务的表现才会受损。这些结果表明，在FC的传入纤维调节手指的位置，这样做部分通过反射机制。当FC中断时，无法控制手指位置会干扰精细运动活动。
Previous studies have reported abnormalities in fine hand and finger movements following interruption of the fasciculus cuneatus (FC) in primates. We report here that many of these deficits could be caused by an inability to actively regulate the position of the finger. Three macaques were trained to maintain the index finger in one position against constant or changing loads. Periodically, torque pulses were used to elicit reflexes in finger muscles. Following unilateral FC lesions, the monkeys failed to adjust finger position during the trials, and the normal M2 long-latency response was absent in the finger muscles. Performance on the task was impaired only in monkeys with complete lesions that included the deep ventral portion of the FC. These results suggest that afferent fibers in the FC regulate finger position, and do so partly through reflexive mechanisms. When the FC is interrupted, the inability to control finger position disturbs fine motor activities.