Disease severity of proliferative lupus nephritis in Maghrebians
Disease severity of proliferative lupus nephritis in Maghrebians
复制标题
DOI：
10.1177/0961203318772016
复制
发表时间：
2018-07-01
期刊：
影响因子：
2.6
通讯作者：
Houssiau, F. A.
中科院分区：
文献类型：
--
作者：
Tamirou, F.;Costedoat-Chalumeau, N.;Houssiau, F. A.
目的探讨马格里布族对狼疮性肾炎的影响。方法回顾性分析了来自7个狼疮中心的194例增殖性狼疮肾炎患者的资料，这些患者分为三组：居住在比利时/法国的欧洲人（E; n=111）；居住在欧洲的马格里布人，如比利时/法国（欧洲；n=43）；以及生活在摩洛哥的马格里布人（MM; n=40）。我们比较了这三组患者的基线表现，但完整的长期结果数据仅适用于E和ME患者。结果狼疮性肾炎的临床和病理特征在E型、ME型和MM型患者中无明显差异。ME患者肾脏复发发生率（54%）高于E患者（29%）
Objective To study the influence of Maghrebian ethnicity on lupus nephritis.Methods We retrospectively reviewed the files of a cohort of 194 patients with proliferative lupus nephritis followed in seven lupus centres belonging to three groups: Europeans living in Belgium/France (E; n=111); Maghrebians living in Europe, in casu Belgium/France (ME; n=43); and Maghrebians living in Morocco (MM; n=40). Baseline presentation was compared between these three groups but complete long-term outcome data were available only for E and ME patients.Results At presentation, the clinical and pathological characteristics of lupus nephritis did not differ between E, ME and MM patients. Renal relapses were more common in ME patients (54%) than in E patients (29%) (P