A carcinogenicity assay of Mirex in Charles River CD rats.
A carcinogenicity assay of Mirex in Charles River CD rats.
复制标题
灭蚁灵对 Charles River CD 大鼠的致癌性测定。
DOI：
10.1093/jnci/58.1.133
复制
发表时间：
1977
期刊：
影响因子：
--
通讯作者：
R. Cypher
中科院分区：
文献类型：
--
作者：
B. Ulland;N. Page;R. Squire;E. Weisburger;R. Cypher
The long-term administration of 50 and 100 ppm of Mirex in the diets of male and female Charles River CD rats was associated with a spectrum of liver lesions, from foci or areas of cellular alteration and neoplastic nodules to hepatocellular carcinoma. Statistically significant numbers of neoplastic nodules were observed in the livers of male rats receiving the high dose. Neoplastic nodules and hepatocellular carcinomas were not observed in control rats.
