High Pressure Michael Addition Catalyzed by Fluoride Ions
High Pressure Michael Addition Catalyzed by Fluoride Ions
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DOI：
10.1002/anie.198107701
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发表时间：
1981-09
影响因子：
--
通讯作者：
K. Matsumoto,
中科院分区：
文献类型：
--
作者：
K. Matsumoto,
如果供体反应中心有较大的取代基，用迈克尔加成法合成具有季碳原子的化合物往往不成功。然而，在高压条件和氟催化下，查尔酮与异丙二酸二乙酯和苯基丙二酸二乙酯的反应收率分别为20%和24%。
The synthesis of compounds having quaternary C atomsby Michael addition is often unsuccessful if the donor reaction center has bulky substituents. However, under high pressure conditions and fluoride catalysis evene.g.chalcone reacts with diethyl isopropylmalonate and diethyl phenylmalonate in 20 and 24% yield, respectively.