Comparison of GEANT4 very low energy cross section models with experimental data in water
Comparison of GEANT4 very low energy cross section models with experimental data in water
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DOI：
10.1118/1.3476457
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发表时间：
2010-09-01
期刊：
影响因子：
3.8
通讯作者：
Zacharatou, C.
中科院分区：
文献类型：
--
作者：
Incerti, S.;Ivanchenko, A.;Zacharatou, C.
目的：GEANT 4通用蒙特卡罗模拟工具包能够模拟电子、氢和氦原子与电荷态（H-0、H+）的物理相互作用过程，（He-0，He+，He 2+），分别在液态水，生物系统的主要组成部分，下降到电子伏特制度和亚微米尺度，为GEANT 4用户提供适用于微剂量学模拟应用的所谓“GEANT 4-DNA”物理模型。最近对相应的软件进行了重新设计，以便为GEANT 4用户提供一种在GEANT 4工具包框架内模拟电磁相互作用的连贯和独特的方法（自GEANT 4版本9.3 beta以来）。这项工作提出了一个定量的比较，这些物理模型与收集的实验数据在水中收集的literature.Methods：之间的密切程度评价的总和微分截面模型，可在GEANT 4工具包的微剂量和实验参考数据进行使用一个专门的统计工具包，包括Kolmogorov-Smirnov统计检验。作者使用在水蒸气中获得的实验数据，因为在液相中的直接测量在文献中还不可用。结果：作者通过定量方法评估了实验数据与GEANT 4微剂量学模型的兼容性。结果表明，在液态水中的微剂量测量是必要的定量评估的有效性的软件实现的液态水相。然而，与现有的实验数据在水蒸气中的比较提供了一个定性的评价模拟模型的可扩展性。现有的参考数据本身应进行严格的解释和选择，因为一些系列表现出显着的偏差从each other.Conclusions：GEANT 4-DNA物理模型中提供的GEANT 4工具包已在本文中进行了比较，可用的实验数据在水蒸气相，以及几个公布的建议的质量阻止功率。这些模型是将GEANT 4蒙特卡罗工具包扩展到模拟电离辐射生物效应的第一步。(c)2010年美国医学物理学家协会。[DOI 10.1118/1.3476457]
Purpose: The GEANT4 general-purpose Monte Carlo simulation toolkit is able to simulate physical interaction processes of electrons, hydrogen and helium atoms with charge states (H-0, H+) and (He-0, He+, He2+), respectively, in liquid water, the main component of biological systems, down to the electron volt regime and the submicrometer scale, providing GEANT4 users with the so-called "GEANT4-DNA" physics models suitable for microdosimetry simulation applications. The corresponding software has been recently re-engineered in order to provide GEANT4 users with a coherent and unique approach to the simulation of electromagnetic interactions within the GEANT4 toolkit framework (since GEANT4 version 9.3 beta). This work presents a quantitative comparison of these physics models with a collection of experimental data in water collected from the literature.Methods: An evaluation of the closeness between the total and differential cross section models available in the GEANT4 toolkit for microdosimetry and experimental reference data is performed using a dedicated statistical toolkit that includes the Kolmogorov-Smirnov statistical test. The authors used experimental data acquired in water vapor as direct measurements in the liquid phase are not yet available in the literature. Comparisons with several recommendations are also presented.Results: The authors have assessed the compatibility of experimental data with GEANT4 microdosimetry models by means of quantitative methods. The results show that microdosimetric measurements in liquid water are necessary to assess quantitatively the validity of the software implementation for the liquid water phase. Nevertheless, a comparison with existing experimental data in water vapor provides a qualitative appreciation of the plausibility of the simulation models. The existing reference data themselves should undergo a critical interpretation and selection, as some of the series exhibit significant deviations from each other.Conclusions: The GEANT4-DNA physics models available in the GEANT4 toolkit have been compared in this article to available experimental data in the water vapor phase as well as to several published recommendations on the mass stopping power. These models represent a first step in the extension of the GEANT4 Monte Carlo toolkit to the simulation of biological effects of ionizing radiation. (c) 2010 American Association of Physicists in Medicine. [DOI: 10.1118/1.3476457]