Specific binding of phorbol esters to nuclei of human promyelocytic leukemia cells.
Specific binding of phorbol esters to nuclei of human promyelocytic leukemia cells.
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佛波酯与人早幼粒细胞白血病细胞核的特异性结合。
DOI：
10.1016/s0006-291x(87)80523-5
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发表时间：
1987
影响因子：
3.1
通讯作者：
Berkow,RL
中科院分区：
文献类型：
--
作者：
Kraft,AS;Appling,C;Berkow,RL
In this report, we demonstrate that HL-60 nuclei isolated in calcium but not EGTA containing buffers specifically bind PE and express approximately 37,000 receptor sites/nucleus. Nuclear phorbol ester binding is lost by isolation in the absence of calcium, but can be repleted by the addition of partially purified protein kinase C and calcium. When HL-60 cells are treated with bryostatin 1, a compound which activates protein kinase C in a similar fashion to phorbol esters but does not induce differentiation of HL-60 cells, and nuclei are isolated in the presence of EGTA, these nuclei continue to bind phorbol esters. These experiments suggest that HL-60 nuclei bind PEin vitro, and that comments that activate protein kinase C may increase nuclear binding of PEin situ.
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胚胎癌细胞中胞浆钙激活磷脂依赖性蛋白激酶活性的表征。
影响因子：
4.8
作者：
A. Kraft;W. Anderson
通讯作者：
W. Anderson
DNA 合成缺失情况下人早幼粒细胞白血病细胞的终末分化
影响因子：
64.8
作者：
G. Rovera;N. Olashaw;P. Meo
通讯作者：
P. Meo
DOI：
10.1016/s0021-9258(18)67134-0
发表时间：
1986-09
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
A. Merrill;A. Sereni;V. Stevens;Y. Hannun;R. Bell;J. M. Kinkade
通讯作者：
A. Merrill;A. Sereni;V. Stevens;Y. Hannun;R. Bell;J. M. Kinkade
佛波二酯诱导人白细胞介素 2 受体的表达和磷酸化。
DOI：
--
发表时间：
1984
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Shackelford,DA;Trowbridge,IS
通讯作者：
Trowbridge,IS
佛波二酯诱导 HL60 早幼粒细胞中核基质蛋白的磷酸化。
影响因子：
4.8
作者：
D. Macfarlane
通讯作者：
D. Macfarlane