Abnormal subjective experiences in schizophrenia: Its relationships with neuropsychological disturbances and frontal signs
Abnormal subjective experiences in schizophrenia: Its relationships with neuropsychological disturbances and frontal signs
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DOI：
10.1007/bf02274900
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发表时间：
1996-02-01
影响因子：
4.7
通讯作者：
Juan, JA
中科院分区：
文献类型：
--
作者：
Cuesta, MJ;Peralta, V;Juan, JA
精神分裂症患者主观体验异常的发生率较高。本研究从这些主观障碍与认知障碍相关的假设开始。为了验证这一假设，对40例根据RDC和DSM-III-R标准诊断为精神分裂症的患者进行了研究。他们是连续入院，因为他们的肿瘤复发。第3版的法兰克福投诉问卷，由作者改编为西班牙语，被用作主观经验的评估工具。8名患者拒绝回答问卷。一个神经心理电池，包括迷你精神状态，从WAIS，本德的视觉运动测试，雷伊的复杂的图形，和线索制作测试的一些子测试，被使用。评价额叶神经系统体征。精神分裂症患者的异常主观经验与神经心理障碍密切相关，在较小程度上，与额叶神经系统体征的强度。用逐步回归法和偏相关分析进行了回归分析。在控制了年龄、性别、教育、缺乏洞察力、抗精神病药物剂量和比哌立定剂量的影响后，主观体验和认知障碍之间的许多显著关系仍然存在。
The prevalence of abnormal subjective experiences is high in schizophrenic patients. This study starts from the hypothesis that these subjective disorders are associated with cognitive disturbances. In order to test this hypothesis a study was carried out on 40 patients who were diagnosed as suffering from schizophrenia according to RDC and DSM-III-R criteria. They were consecutively admitted due to a recrudescence of their symptomatology. Version 3 of the Frankfurt Complaint Questionnaire, adapted for Spanish by the authors, was used as an instrument for the assessment of subjective experiences. Eight patients refused to answer the questionnaire. A neuropsychological battery, including the Mini-Mental State, some subtests from the WAIS, Bender's visual-motor test, Rey's Complex Figure, and the Trail Making Test, was used. Frontal neurological signs were evaluated. The abnormal subjective experiences of schizophrenics presented a close association with neuropsychological disturbances and, to a lesser degree, of intensity with frontal neurological signs. Regression analyses by means of stepwise method and partial correlation analyses were undertaken. Many significant relationships between subjective experiences and cognitive disturbances persisted after controlling the influence of age, gender, education, lack of insight, neuroleptic doses, and biperidene doses.