BMI compared with central obesity indicators in relation to diabetes and hypertension in Asians
BMI compared with central obesity indicators in relation to diabetes and hypertension in Asians
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DOI：
10.1038/oby.2008.73
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发表时间：
2008-07-01
期刊：
影响因子：
6.9
通讯作者：
Nyamdorj, R.
中科院分区：
文献类型：
--
作者：
Nyamdorj, R.
目的：比较BMI与腰围（WC）、腰臀比（WHR）和腰高比（WSR）与糖尿病或高血压的相关性。（糖尿病流行病学：亚洲诊断标准协作分析）研究，包括9，095名男性和11，732名女性，年龄35-74岁，结果：男性（女性）糖尿病患者1s.d. BMI、WC、WHR和WSR的增加分别为1.52（1.59）、1.54（1.70）、1.53（1.50）和1.62（1.70）;高血压的相应OR分别为1.68（1.55）、1.66（1.51）、1.45（1.28）和1.63（1.50）。配对同质性检验（BMI分别与三项指标）经年龄和队列调整后显示，男性糖尿病与WSR的相关性强于BMI（P = 0.001），而女性糖尿病与WC和WSR的相关性强于BMI（均P < 0.05）。男性高血压与BMI的相关性强于WHR（P < 0.001），女性高血压与BMI的相关性强于WHR（P < 0.001）、WSR（P < 0.01）和WC（P < 0.05）。经年龄和队列校正的受试者工作特征（ROC）曲线下面积对于WSR 0.735的糖尿病略大男性（女性）为0.748，女性为0.749（仅限女性）BMI 0.725 BMI为0.760时，高血压患者的BMI值大于0.742 WSR（0.766）高于WHR（0.751），但两者的95%CI均重叠。讨论：WSR与糖尿病的相关性强于BMI，但这些指标与亚洲人高血压的相关性同样强。
Objective: To compare BMI with waist circumference (WC), waist-to-hip ratio ( WHR), and waist-to-stature ratio (WSR) in association with diabetes or hypertension.Methods and Procedures: Cross-sectional data from 16 cohorts from the DECODA ( Diabetes Epidemiology: Collaborative Analysis of Diagnostic criteria in Asia) study, comprising 9,095 men and 11,732 women, aged 35-74 years, of different ethnicities were included in this meta-analysis.Results: Age-adjusted odds ratios (ORs) for diabetes in men ( women) for 1 s.d. increase in BMI, WC, WHR, and WSR were 1.52 (1.59), 1.54 (1.70), 1.53 (1.50), and 1.62 ( 1.70), respectively; and the corresponding ORs for hypertension were 1.68 (1.55), 1.66 (1.51), 1.45 (1.28), and 1.63 ( 1.50). Paired homogeneity tests ( BMI with each of the three) adjusted for age and cohort showed that diabetes had stronger association with WSR than BMI (P = 0.001) in men but with WC and WSR than BMI (both P < 0.05) in women. Hypertension had stronger association with BMI than WHR in men ( P < 0.001) and had the strongest with BMI than the others ( WHR P < 0.001; WSR P < 0.01; and WC P < 0.05) in women. Areas under the receiver operating characteristic (ROC) curves adjusted for age and cohort were slightly larger for diabetes for WSR 0.735 (0.748) in men (women) and WC 0.749 ( women only) than BMI 0.725 (0.742) while for hypertension larger for BMI 0.760 (0.766) than WHR 0.748 (0.751), but their 95% CIs were all overlapped.Discussion: WSR was stronger than BMI in association with diabetes, but these indicators were equally strongly associated with hypertension in Asians.