THEORY OF AGGREGATION IN SOLUTION .1. GENERAL EQUATIONS AND APPLICATION TO STACKING OF BASES, NUCLEOSIDES, ETC
THEORY OF AGGREGATION IN SOLUTION .1. GENERAL EQUATIONS AND APPLICATION TO STACKING OF BASES, NUCLEOSIDES, ETC
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DOI：
10.1002/bip.1973.360120608
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发表时间：
1973-01-01
期刊：
影响因子：
2.9
通讯作者：
CHEN, Y
中科院分区：
文献类型：
--
作者：
HILL, TL;CHEN, Y
早期的理论工作聚集在不完美的气体和蛋白质分子的解决方案在这里重新制定这样一种方式，适用于一些聚集系统的解决方案。对于“渗透”溶液，该理论最容易发展。原则上，它是精确的，特别是不像通常那样将骨料视为理想的混合物。如果渗透维里系数在特定情况下难以测量，则有必要将这些系数与更常规的“恒压”溶液的性质联系起来。在最后三节中使用了一个重要的特殊情况作为例子：碱基、核苷等的堆叠，由统计力学模型表示，其中聚集体类似于棋盘格的垂直堆叠。
Earlier theoretical work on aggregation in imperfect gases and in solutions of protein molecules is reformulated here in such a way as to be applicable to a number of aggregation systems in solution. The theory is most easily developed for an “osmotic” solution. It is exact, in principle, and in particular does not treat the aggregates as an ideal mixture as is usually done. If osmotic virial coefficients are diffcult to measure in a particular case, it is then necessary to relate these coefficients to properties of the more conventional “constant pressure” solution. An important special case is used as an example in the last three sections: The stacking of bases, nucleosides, etc., is represented by a statistical mecchanical model in which the aggregates resemble vertical stacks of checkers.