Ontogeny of β-endorphin and cortisol in the plasma of children and adolescents
Ontogeny of β-endorphin and cortisol in the plasma of children and adolescents
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儿童和青少年血浆中β-内啡肽和皮质醇的个体发育
DOI：
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发表时间：
1988
期刊：
影响因子：
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通讯作者：
S. Josephs
中科院分区：
文献类型：
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作者：
Herman Bh;A. Arthur;M. K. Hammock;S. Josephs
本文研究了不同民族正常儿童（3-11岁）和青少年（12-18岁）血浆β-内啡肽（B-E）和皮质醇浓度的个体发生。B-E [男性（n = 88），7.19 ± 0.39（±se）pmol/L;女性（n = 73），6.80 ± 0.50 pmol/L]或皮质醇[男性（n = 87），383 ± 14 nmol/L;女性（n = 69），359 ± 20 nmol/L]的早晨血浆浓度在性别或年龄方面无显著差异。血浆B-E和皮质醇浓度之间存在小但显著的正相关。当静脉穿刺后立即采样时，在静脉穿刺过程中哭泣的儿童与没有哭泣的儿童相比，血浆B-E或皮质醇浓度没有显著差异。这些数据表明，早晨血浆B-E和皮质醇浓度在整个儿童期、青春期和成年早期是恒定的。
The ontogeny of plasma β-endorphin (B-E) and cortisol concentrations was studied in normal children (3–11 yr old) and adolescents (12–18 yr old) of several ethnic backgrounds. The morning plasma concentrations did not significantly differ as a function of sex or age for either B-E [males (n = 88), 7.19 ± 0.39 (±se) pmol/L; females (n = 73), 6.80 ± 0.50 pmol/L] or cortisol [males (n = 87), 383 ± 14 nmol/L; females (n = 69), 359 ± 20 nmol/L]. There was a small but significant positive correlation between plasma B-E and cortisol concentrations. When sampled immediately after venipuncture, there were no significant differences in the plasma B-E or cortisol concentrations of children who cried during venipuncture compared with those who did not. These data suggest that morning plasma B-E and cortisol concentrations are constant throughout childhood, adolescence, and into early adulthood.