Bronchial circulation in asthma.
Bronchial circulation in asthma.
复制标题
哮喘中的支气管循环。
DOI：
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
Adam Wanner
中科院分区：
文献类型：
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作者：
Horst Baier;W. M. Long;Adam Wanner
尽管支气管循环响应各种先天性和后天性心肺疾病的解剖学变化已得到充分描述，但对其功能反应却知之甚少。越来越多的证据表明，支气管循环在高反应性气道疾病的病理生理学中发挥着重要作用。支气管血管系统似乎参与介质往返于气道壁目标组织的运输、可能导致气流阻塞的气道壁水肿的发展以及气管支气管树中的热和水交换。尽管我们目前对这些功能的理解相当粗略，但已经足以概述支气管（即体循环）对支气管哮喘机制的贡献。
Whereas the anatomical changes of the bronchial circulation in response to a wide variety of congenital and acquired cardiopulmonary diseases have been well described, little is known about its functional response. There is growing evidence that the bronchial circulation plays a major role in the pathophysiology of hyperreactive airway disease. The bronchial vascular system appears to be involved in mediator transport to and from target tissues in the airway wall, in the development of airway wall edema which may contribute to airflow obstruction, and in heat and water exchange in the tracheobronchial tree. Although our current understanding of these functions is rather sketchy, enough is known to outline the contributions of the bronchial, i.e. the systemic circulation to the mechanisms of bronchial asthma.