Morphometric analysis of the components of the neonatal and the adult rat testis interstitium.
Morphometric analysis of the components of the neonatal and the adult rat testis interstitium.
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新生儿和成年大鼠睾丸间质成分的形态测量分析。
DOI：
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发表时间：
1987
影响因子：
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通讯作者：
D. Kretser
中科院分区：
文献类型：
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作者：
S. Mendis‐Handagama;G. Risbridger;D. Kretser
胎鼠睾丸中的间质细胞在出生时仍然存在，并且根据其体积密度（v/v%）随年龄的降低，推测它们在出生后立即开始退化。在这项研究中，定量研究了出生后1、5、10、15、20和90天大鼠睾丸的睾丸组织：后者被认为是成年大鼠。结缔组织细胞和血管的绝对体积随着年龄的增长而增加。巨噬细胞和淋巴间隙的绝对体积在90天时大于任何其他年龄。胎儿睾丸间质细胞的绝对体积从1天到15天没有变化，尽管每个睾丸所占的体积百分比下降。每个睾丸的胎儿Leydig细胞的数量没有下降，从第1-20天，虽然在第20天的平均胎儿Leydig细胞的体积小于在早期年龄（1-15天）。成年Leydig细胞在第10天被识别，并且它们的绝对体积和每个睾丸的数量从15天增加到90天。成人Leydig细胞在形态上类似于胎儿Leydig细胞在20天，除了细胞质脂质体积减少。
Leydig cells in the foetal rat testis are still present at birth and it has been hypothesized that they commence to degenerate immediately after birth, based on the decrease in their volume density (v/v%) with age. In this study the interstitium of the rat testis was studied quantitatively at 1, 5, 10, 15, 20 and 90 days after birth: the latter are considered to be adults. The absolute volumes of connective tissue cells and blood vessels increased with age. The absolute volumes of macrophages and lymphatic spaces were greater at 90 days than at any other age. The absolute volume of foetal Leydig cells per testis was unchanged from 1 to 15 days, despite a decrease in the % volume occupied per testis. The number of foetal Leydig cells per testis did not decline from days 1-20 although on day 20 an average foetal Leydig cell was smaller in volume than at earlier ages (days 1-15). Adult Leydig cells were recognized at day 10 and their absolute volume and number per testis increased from 15 to 90 days. Adult Leydig cells were similar in morphology to foetal Leydig cells at 20 days except for a reduced volume of cytoplasmic lipid.