CHARACTERISTICS OF AIRBORNE PARTICLES ASSOCIATED WITH ANIMAL ALLERGY IN LABORATORY WORKERS
CHARACTERISTICS OF AIRBORNE PARTICLES ASSOCIATED WITH ANIMAL ALLERGY IN LABORATORY WORKERS
复制标题
与实验室工作人员动物过敏相关的空气传播颗粒的特征
DOI：
10.1093/annhyg/32.inhaled_particles_vi.435
复制
发表时间：
1988
影响因子：
--
通讯作者：
R. Evans
中科院分区：
文献类型：
--
作者：
M. Corn;A. Koegel;T. Hall;A. Scott;C. Newill;R. Evans
在实验动物设施中获取区域和个人样本，以确定大鼠衍生的空气过敏原的浓度和相关的颗粒尺寸分布。通过间接酶联免疫吸附测定（ELISA）评估大鼠尿液和唾液抗原的数量。采样区域包括老鼠饲养室、邻近走廊、动物实验室和非动物控制场所。发现NG/m 3 量的抗原与空气中的颗粒相关，其重量与重量之比约为1/1000。空气中抗原浓度最高的地方是住宅区，夜间浓度显着增加。居住区和动物实验室的个人样本产生的空气传播抗原浓度比来自区域样本的相应结果高出大约一个数量级。尿液和唾液抗原与空气动力学当量直径 (AED) μm 至 > 24 μm AED 大小的颗粒相关。大约 70%（按重量计）与可吸入颗粒 (μ m AED) 有关。
Area and personal samples were obtained in experimental animal facilities to determine concentrations of rat derived airborne allergens and the associated particle size distributions. Quantities of rat urinary and salivary antigens were assessed by indirect enzyme-linked immunosorbent assay (ELISA). Areas sampled included rat housing rooms, adjacent corridors, animal laboratories, and non-animal control locations. Ng/m 3 quantities of antigen were found to be associated with airborne particles in a weight-to-weight ratio of approximately 1/1000. The highest airborne antigen concentrations occurred in housing locations, with significant increases occurring during night hours. Personal samples in housing areas and animal laboratories yielded airborne antigen concentrations approximately one order of magnitude higher than corresponding results derived from area samples. Urinary and salivary antigens were associated with particles from μ m Aerodynamic Equivalent Diameter (AED) to > 24 μ m AED in size. Approximately 70% by weight was associated with respirable particles ( μ m AED).
在实验动物设施中对空气中的小鼠过敏原进行免疫化学测量。
DOI：
10.1016/0091-6749(82)90177-4
发表时间：
1982
期刊：
The Journal of allergy and clinical immunology
影响因子：
--
作者：
Twiggs,JT;Agarwal,MK;Dahlberg,MJ;Yunginger,JW
通讯作者：
Yunginger,JW