Impact of COVID-19 pandemic on HIV viremia: a single-center cohort study in northern Italy.
Impact of COVID-19 pandemic on HIV viremia: a single-center cohort study in northern Italy.
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DOI：
10.1186/s12981-021-00355-x
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发表时间：
2021-06-04
影响因子：
2.2
通讯作者：
Quiros-Roldan E
中科院分区：
文献类型：
--
作者：
Izzo I;Carriero C;Gardini G;Fumarola B;Chiari E;Castelli F;Quiros-Roldan E
意大利北部的布雷西亚省是新冠肺炎疫情最严重的重灾区之一。布雷西亚特别平民医院传染病科面对大量重症COVID-19住院患者，并确保我们积极跟进的近4000名艾滋病毒感染门诊患者的持续护理。在最近的一篇论文中，我们描述了大流行对我们的艾滋病毒队列持续护理的影响，包括错过就诊的次数、新的艾滋病毒诊断的次数、ART（抗逆转录病毒治疗）分配的下降以及由于SARS-CoV-2感染而住院的艾滋病毒患者的数量。在这篇简短的通讯中，我们用大流行前和大流行期间同一队列的HIV血浆病毒血症数据完成了之前的文章。我们考虑了所有在2019年3月1日至11月30日的时间窗口内接受稳定抗逆转录病毒治疗至少6个月且至少有一种可用的HIV病毒血症的HIV患者，以及另一组具有相同两个必备条件但处于COVID-19期间（2020年3月1日至5月31日和2020年6月1日至11月30日）的不同时间窗口的HIV患者。对于COVID-19期间病毒血症（PV）阳性的患者，我们还报告了PV前后的病毒载量（VL）值。结果：新冠肺炎期间PV患者比例低于上年（2.8% vs . 7%）。我们的门诊患者中只有1%的人确实遭受了大流行，就失去了先前的病毒抑制而言。我们为限制这一流行病对我们的艾滋病毒门诊病人的影响所作的努力有效地确保了对艾滋病毒的持续护理。
Brescia Province, northern Italy, was one of the worst epicenters of the COVID-19 pandemic. The division of infectious diseases of ASST (Azienda Socio Sanitaria Territoriale) Spedali Civili Hospital of Brescia had to face a great number of inpatients with severe COVID-19 infection and to ensure the continuum of care for almost 4000 outpatients with HIV infection actively followed by us. In a recent manuscript we described the impact of the pandemic on continuum of care in our HIV cohort expressed as number of missed visits, number of new HIV diagnosis, drop in ART (antiretroviral therapy) dispensation and number of hospitalized HIV patients due to SARS-CoV-2 infection. In this short communication, we completed the previous article with data of HIV plasmatic viremia of the same cohort before and during pandemic. We considered all HIV-patients in stable ART for at least 6 months and with at least 1 available HIV viremia in the time window March 01–November 30, 2019, and another group of HIV patients with the same two requisites but in different time windows of the COVID-19 period (March 01–May 31, 2020, and June 01–November 30, 2020). For patients with positive viremia (PV) during COVID-19 period, we reported also the values of viral load (VL) just before and after PV. Results: the percentage of patients with PV during COVID-19 period was lower than the previous year (2.8% vs 7%). Only 1% of our outpatients surely suffered from pandemic in term of loss of previous viral suppression. Our efforts to limit the impact of pandemic on our HIV outpatients were effective to ensure HIV continuum of care.
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影响因子：
6
作者：
Rebeiro PF;Duda SN;Wools-Kaloustian KK;Nash D;Althoff KN;International epidemiology Databases to Evaluate AIDS (IeDEA)
通讯作者：
International epidemiology Databases to Evaluate AIDS (IeDEA)
影响因子：
3.8
作者：
Tshikung, Olivier Nawej;Smit, Mikaela;Calmy, Alexandra
通讯作者：
Calmy, Alexandra
影响因子：
2.2
作者：
Quiros-Roldan E;Magro P;Carriero C;Chiesa A;El Hamad I;Tratta E;Fazio R;Formenti B;Castelli F
通讯作者：
Castelli F
DOI：
10.1097/qad.0000000000002677
发表时间：
2020-12-01
期刊：
AIDS (London, England)
影响因子：
--
作者：
Spinelli MA;Hickey MD;Glidden DV;Nguyen JQ;Oskarsson JJ;Havlir D;Gandhi M
通讯作者：
Gandhi M
影响因子：
4.5
作者：
Amimo, Floriano;Lambert, Ben;Magit, Anthony
通讯作者：
Magit, Anthony