Epidemiological Characteristics of Vascular Dementia among Community-Dwellings Aged 55 Plus in Mainland China: A Meta-analysis of Studies Published between 1980 and 2011
Epidemiological Characteristics of Vascular Dementia among Community-Dwellings Aged 55 Plus in Mainland China: A Meta-analysis of Studies Published between 1980 and 2011
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发表时间：
2013
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通讯作者：
Q. Yan
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作者：
Q. Yan
目的 分析1980—2011年中国大陆55岁及以上人群血管性痴呆（VD）的发病率、患病率和死亡率。方法利用中国生物医学文献数据库（CBM）、中国期刊全文数据库（CNKI）、中国科技期刊数据库（CNKI）、中国科技期刊数据库，手工和在线检索1980—2011年发表的期刊上血管性痴呆（VD）的流行病学调查资料。 （VIP）和万方数据库。英文期刊中报道的内容是使用 PubMed、爱思唯尔科学书目数据库 (EMBASE) 和 Cochrane 图书馆进行识别的。根据同质性统计检验，采用随机效应模型。结果纳入62项研究，收集统计信息进行系统分析。 VD的患病率、发病率和死亡率合计分别为0.8%（95%[置信区间，CI]0.7%～0.9%）、0.27（95%CI 0.20～0.34）/100人年和14.6（95%CI 6.7～22.4）/100人年。 1980年至2011年间，VD患病率缓慢上升，在中国北方和城市更高。老年人、男性和文盲人群中 VD 的患病率较高，其发病率相同。结论自1980年以来VD患病率缓慢上升，南北、城乡地区差异明显。 VD 的患病率和发病率可能受年龄、性别和教育程度的影响。
Objective To analyze the incidence, prevalence and mortality of vascular dementia (VD) among the population aged 55 years and older in mainland China from 1980 to 2011. Methods Epidemiological investigations on VD published in journals and covering the period from 1980 to 2011 were identified manually and online by using the Chinese BioMedical Literature Database (CBM), the Chinese Journal Full-text Database (CNKI), the Chinese Science-Technology Periodical Database (VIP) and Wanfang Database. Those reported in English journals were identified using PubMed, Elsevier Science Bibliographic Databases (EMBASE) and the Cochrane library. The random effects model was employed according to statistical test of homogeneity. Results Sixty-two studies were included, the statistical information of which was collected for systematic analysis. The pooled prevalence, incidence and mortality of VD was 0.8% (95% [confidence interval, CI] 0.7%～0.9%), 0.27 (95%CI 0.20～0.34)/100 person-year and 14.6 (95%CI 6.7～22.4)/100 person-year. The prevalence of VD was slowly rising between 1980 and 2011 and higher in northern China and urban. There was a higher prevalence of VD in the population who was older, male and illiterate and the same for its incidence. Conclusion The prevalence of VD has slowly risen since 1980 and is obviously different betweenthe North and South, urban and rural district. The prevalence and incidence of VD may be affected by age, sex and education.