Material and Structural Modeling Aspects of Brain Tissue Deformation under Dynamic Loads
Material and Structural Modeling Aspects of Brain Tissue Deformation under Dynamic Loads
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DOI：
10.3390/ma12020271
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发表时间：
2019-01-02
期刊：
影响因子：
3.4
通讯作者：
Bedzinski, Romuald
中科院分区：
文献类型：
--
作者：
Ratajczak, Monika;Ptak, Mariusz;Bedzinski, Romuald
这项工作的目的是评估在动态载荷条件下脑组织的结构和材料建模的多种方法。材料建模的当前技术改进导致了文献中描述的各种方法。然而，用于确定大脑特征的方法并不总是被陈述或明确定义，材料数据更加分散。因此，本文中描述的研究明确强调了数字大脑模型的发展方向。这项研究的一个重要组成部分是基于医学成像方法开发大脑的数值模型。这种方法使作者能够评估由机械载荷的影响引起的脑组织的机械和几何参数的变化。所开发的模型进行了验证，通过比较与实验研究，在文献中描述的死后人类受试者，以及通过数值试验。基于当前的研究，作者确定了脑组织建模的重要方面，这些方面影响了动态分析中大脑实际生物力学响应的评估。
The aim of this work was to assess the numerous approaches to structural and material modeling of brain tissue under dynamic loading conditions. The current technological improvements in material modeling have led to various approaches described in the literature. However, the methods used for the determination of the brain's characteristics have not always been stated or clearly defined and material data are even more scattered. Thus, the research described in this paper explicitly underlines directions for the development of numerical brain models. An important element of this research is the development of a numerical model of the brain based on medical imaging methods. This approach allowed the authors to assess the changes in the mechanical and geometrical parameters of brain tissue caused by the impact of mechanical loads. The developed model was verified through comparison with experimental studies on post-mortem human subjects described in the literature, as well as through numerical tests. Based on the current research, the authors identified important aspects of the modeling of brain tissue that influence the assessment of the actual biomechanical response of the brain for dynamic analyses.