NSP1 of the GRAS protein family is essential for rhizobial Nod factor-induced transcription
NSP1 of the GRAS protein family is essential for rhizobial Nod factor-induced transcription
复制标题
DOI：
10.1126/science.1111025
复制
发表时间：
2005-06-17
期刊：
影响因子：
56.9
通讯作者：
Geurts, R
中科院分区：
文献类型：
--
作者：
Smit, P;Raedts, J;Geurts, R
根瘤因子诱导豆科宿主中许多基因的表达，并启动发育过程，导致根瘤形成。在这里，我们报告的苜蓿GRAS型蛋白结瘤信号通路1（NSP1），这是必不可少的所有已知的结瘤因子诱导的基因表达的变化的鉴定。NSP1是组成型表达的，因此它作为一个主要的转录调节因子介导所有已知的Nod因子诱导的转录反应，因此，我们将其命名为Nod因子反应因子。
Rhizobial Nod factors induce in their legume hosts the expression of many genes and set in motion developmental processes leading to root nodule formation. Here we report the identification of the Medicago GRAS-type protein Nodulation signaling pathway 1 (NSP1), which is essential for all known Nod factor-induced changes in gene expression. NSP1 is constitutively expressed, and so it acts as a primary transcriptional regulator mediating all known Nod factor-induced transcriptional responses, and therefore, we named it a Nod factor response factor.