A Cross-Sectional Comparison of the Prevalence of Obstructive Sleep Apnea Symptoms in Adults With Down Syndrome in Scotland and Japan
A Cross-Sectional Comparison of the Prevalence of Obstructive Sleep Apnea Symptoms in Adults With Down Syndrome in Scotland and Japan
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DOI：
10.1352/1944-7558-125.4.260
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发表时间：
2020-07-01
影响因子：
2.1
通讯作者：
Ando, Shin-ichi
中科院分区：
文献类型：
--
作者：
Hill, Elizabeth A.;Sawatari, Hiroyuki;Ando, Shin-ichi
在西方人群中进行的小型研究报告称，患有唐氏综合征的成年人中阻塞性睡眠呼吸暂停（OSA）的患病率很高。迄今为止，尚未探讨种族差异。在苏格兰和日本，向2,752名年龄≥ 16岁的唐氏综合征成年人发送了一份问卷（789份有效问卷），根据报告的症状估计了OSA的患病率。症状在这两个国家都很常见，打鼾（p = 0.001）和觉醒（p = 0.04）在日本更普遍。两个国家唐氏综合征成人的OSA患病率估计值相似，与一般成人人群相比有所增加（苏格兰为19.6%，日本为14.3%; p = 0.08），尽管BMI是一个混杂因素。诊断和治疗OSA的建议在成人唐氏综合征，无论种族。
Small studies in Western populations report a high prevalence of obstructive sleep apnea (OSA) in adults with Down syndrome. To date, ethnic differences have not been explored. A questionnaire sent to 2,752 adults with Down syndrome aged >= 16 years in Scotland and Japan (789 valid responses) estimated OSA prevalence based on reported symptoms. Symptoms were common in both countries, with snoring (p = 0.001) and arousals (p = 0.04) more prevalent in Japan. Estimated OSA prevalence in adults with Down syndrome was similar in the two countries, and raised in comparison with the general adult population (19.6% in Scotland and 14.3% in Japan; p = 0.08), though BMI was a confounder. Identification and treatment of OSA is recommended in adults with Down syndrome, regardless of ethnicity.