Factors Associated With Long-Term Weight Loss Following Bariatric Surgery Using 2 Methods for Repeated Measures Analysis.
Factors Associated With Long-Term Weight Loss Following Bariatric Surgery Using 2 Methods for Repeated Measures Analysis.
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使用 2 种方法进行重复测量分析与减肥手术后长期体重减轻相关的因素。
DOI：
10.1093/aje/kwv039
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发表时间：
2015
影响因子：
5
通讯作者：
Rasmussen-Torvik,LauraJ
中科院分区：
文献类型：
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作者：
Baldridge,AbigailS;Pacheco,JenniferA;Aufox,SharonA;Kim,Kwang-YounA;Silverstein,JC;Denham,W;Hungness,E;Smith,MaureenE;Allen,NorrinaB;Greenland,Philip;Rasmussen-Torvik,LauraJ
我们使用了来自NUgene项目（2002-2013）中162例患者的电子健康记录数据，以确定与Roux-en-Y胃旁路手术后长期（1至9.5（平均= 5.6）年）体重减轻相关的人口统计学因素。99例（61.1%）患者自我报告为白色，63例（38.9%）患者自我报告为黑人、混血或缺失人种。术后1年的平均体重减轻百分比为-33.4%（标准差9.3），末次随访时为-30.7%（标准差12.5）。我们使用线性混合和半参数轨迹模型来检验手术和人口统计学因素（身高、手术年龄、手术体重、手术体重指数、婚姻状况、性别、教育水平、部位、国际疾病分类代码、现行手术术语代码、西班牙裔种族和自我报告的种族）与长期体重减轻百分比和体重减轻模式的相关性。我们发现，与白色人种相比，黑人、混血和缺失人种（合并）的体重减轻百分比降低了-4.31%（95%置信区间：-7.30，-1.32），并且不太可能有更高和持续的体重减轻百分比（P= 0.04）。我们还发现，不太肥胖的患者不太可能有更高和持续的体重减轻百分比（P= 0.01）。这些发现可能有助于患者在减肥手术后设定期望。
We used electronic health record data from 162 patients enrolled in the NUgene Project (2002–2013) to determine demographic factors associated with long-term (from 1 to up to 9.5 (mean = 5.6) years) weight loss following Roux-en-Y gastric bypass surgery. Ninety-nine (61.1%) patients self-reported white, and 63 (38.9%) self-reported black, mixed, or missing race. The average percent weight loss was −33.4% (standard deviation, 9.3) at 1 year after surgery and −30.7% (standard deviation, 12.5) at the last follow-up point. We used linear mixed and semiparametric trajectory models to test the association of surgical and demographic factors (height, surgery age, surgery weight, surgery body mass index, marital status, sex, educational level, site,International Classification of Diseasescode,Current Procedural Terminologycode, Hispanic ethnicity, and self-reported race) with long-term percent weight loss and pattern of weight loss. We found that black, mixed, and missing races (combined) in comparison with white race were associated with a decreased percent weight loss of −4.31% (95% confidence interval: −7.30, −1.32) and were less likely to have higher and sustained percent weight loss (P= 0.04). We also found that less obese patients were less likely to have higher and sustained percent weight loss (P= 0.01). These findings may be helpful to patients in setting expectations after weight loss surgery.