The effects of a pacifying stimulus on behavioral and adrenocortical responses to circumcision in the newborn.
The effects of a pacifying stimulus on behavioral and adrenocortical responses to circumcision in the newborn.
复制标题
安抚刺激对新生儿包皮环切的行为和肾上腺皮质反应的影响。
DOI：
10.1097/00004583-198401000-00005
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发表时间：
1984
期刊：
影响因子：
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通讯作者：
Steve Malone
中科院分区：
文献类型：
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作者：
Megan R. Gunnar;Robert O. Fisch;Steve Malone
18名健康男性新生儿，2-5天大，是本研究的对象，研究安抚奶嘴对新生儿包皮环切行为和肾上腺皮质反应的影响。一半的受试者被随机分配到一个条件，在这个条件下，他们被鼓励在包皮环切过程中吮吸安抚奶嘴，而另一半则被分配到一个没有安抚奶嘴的控制条件。在包皮环切术前、中、后各1/2小时进行行为观察；而在包皮环切术前和30分钟后立即采集血清皮质醇测定的血样。结果显示，用安抚奶嘴刺激新生儿可以减少约40%的哭闹。然而，减少哭泣对肾上腺皮质反应没有显著影响。血清皮质醇的升高预测包皮环切术后的平均行为状态，而包皮环切术中的哭泣则没有。此外，有证据表明新生儿肾上腺皮质系统对手术程序的变化很敏感。结果表明，在研究人类新生儿的压力和应对方面，获得行为和激素系统的数据是很重要的。
Eighteen, healthy male newborns, 2–5 days old, were subjects in this study of the effects of a pacifier on the newborn's behavioral and adrenocortical responses to circumcision. Half of the subjects were randomly assigned to a condition in which they were encouraged to suck on a pacifier during circumcision, while half served in a no pacifier, control condition. Behavioral observations were made for 1/2 hour before, during, and after circumcision; while blood samples for serum cortisol determination were obtained immediately before circumcision and 30 min later. The results showed that stimulating the newborn with the pacifier reduced crying by about 40%. Reducing crying, however, had no significant effect on the adrenocortical response. Elevations of serum cortisol predicted average behavioral state following circumcision, whereas crying during circumcision did not. Furthermore, there was evidence that the neonatal adrenocortical system was sensitive to variations in surgical procedures. The results indicate the importance of obtaining data on both behavioral and hormonal systems in studies of stress and coping in human newborns.