Validation of a real-time bladder sensation meter during oral hydration in healthy adults: Repeatability and effects of fill rate and ultrasound probe pressure.
Validation of a real-time bladder sensation meter during oral hydration in healthy adults: Repeatability and effects of fill rate and ultrasound probe pressure.
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健康成人口服补水期间实时膀胱感觉计的验证：填充率和超声探头压力的重复性和影响。
DOI：
10.1111/luts.12275
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发表时间：
2019
期刊：
影响因子：
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通讯作者：
Klausner,AdamP
中科院分区：
文献类型：
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作者：
Sheen,Derek;Kolli,Hiren;Nagle,AnnaS;Cullingsworth,Zachary;Vinod,NaomiN;Naimi,HameedaA;DeWachter,StefanG;Mazzeo,SuzanneE;Stothers,Lynn;Speich,JohnE;Klausner,AdamP
目的：一种非侵入性的方案，利用三维超声和感觉仪来描述实时膀胱感觉。本研究通过测量填充率和超声探头压力对口服水化的影响来研究该方案。方法招募无尿路症状的健康志愿者（基于国际尿失禁咨询问卷对膀胱过度活动调查）进行口服水合研究。在两个完整的补空周期中，参与者喝了2升佳得乐G2（佳得乐公司，伊利诺伊州芝加哥），并使用触摸屏感觉仪记录实时膀胱感觉（0% - 100%）。研究重复了三次，每周一次（访问A， B和C）。在就诊A和B中，超声每5分钟测量一次膀胱体积。C室不使用超声，除非是100%的容量。访问B的体积数据用于估计访问c中整个填充的体积。为每个填充生成感觉-容量曲线以进行比较分析。结果10名参与者完成了3次就诊（共60次）。填充率的增加导致整个填充过程的感觉下降，超声探头压力导致感觉增加。在使用感觉计进行训练之前，参与者在访问A的第1次访问中报告了低音量时更高的感觉。间歇超声的感觉曲线显示在A和b次访问中填充2的重复性。填充率和超声探头压力影响口服水合作用时的实时膀胱感觉。结论：本研究证实了在超声辅助下两次口服水合治疗过程中实时膀胱感觉的可重复性。
ObjectivesA non‐invasive protocol was previously developed using three‐dimensional ultrasound and a sensation meter to characterize real‐time bladder sensation. This study the protocol by measuring the effects of fill rateand ultrasound probe pressure during oral hydration.MethodsHealthy volunteers with no urinary symptoms (based on International Consultation on Incontinence Questionnaire on Overactive Bladder surveys) were recruited into an oral hydration study. Throughout two complete fill–void cycles, participants drank 2 L Gatorade G2 (The Gatorade Company, Inc., Chicago, Illinois) and used a touch‐screen sensation meter to record real‐time bladder sensation (0%‐100%). The study was repeated three times, once per week (Visits A, B, and C). In Visits A and B, ultrasound was used to measure bladder volume every 5 minutes. Ultrasound was not used in Visit C except at 100% capacity. Volume data from Visit B were used to estimate volumes throughout the fills in Visit C. Sensation–capacity curves were generated for each fill for comparative analysis.ResultsTen participants completed three visits (60 total fills). Increased fill rate led to decreased sensation throughout filling, andultrasound probe pressure led to increased sensation. Participants reported higher sensation at low volumes during Fill 1 of Visit A before training with the sensation meter. Sensation curves with intermittent ultrasound showed repeatability for Fill 2 in Visits A and B. Fill rate and ultrasound probe pressure affect real‐time bladder sensation during oral hydration.ConclusionsThis study demonstrated repeatability of real‐time bladder sensation during a two‐fill oral hydration protocol with ultrasound.