iTagPlot: an accurate computation and interactive drawing tool for tag density plot.
iTagPlot: an accurate computation and interactive drawing tool for tag density plot.
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iTagPlot：标签密度图的精确计算和交互式绘图工具。
DOI：
10.1093/bioinformatics/btv166
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
Choi,Jeong-Hyeon
中科院分区：
文献类型：
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作者：
Kim,Sung-Hwan;Ezenwoye,Onyeka;Cho,Hwan-Gue;Robertson,KeithD;Choi,Jeong-Hyeon
动机：标签密度图是非常重要的，直观地揭示生物现象，从捕获为基础的测序数据，通过可视化的归一化读取深度region.Results：我们已经开发了iTagPlot计算标签密度跨功能的功能，并行使用多核和网格引擎，并在图形用户界面中交互式地探索它。它允许我们通过基于生物功能和测量、汇总统计和无监督聚类定义组来对特征进行分层。可用性和实施：http://sourceforge.net/projects/itagplot/.Contact:jechoi@gru.edu和jeochoi@gmail. com补充信息：补充数据可在Bioinformaticsonline获得。
Motivation:Tag density plots are very important to intuitively reveal biological phenomena from capture-based sequencing data by visualizing the normalized read depth in a region.Results:We have developed iTagPlot to compute tag density across functional features in parallel using multicores and a grid engine and to interactively explore it in a graphical user interface. It allows us to stratify features by defining groups based on biological function and measurement, summary statistics and unsupervised clustering.Availability and implementation:http://sourceforge.net/projects/itagplot/.Contact:jechoi@gru.edu and jeochoi@gmail.comSupplementary information:Supplementary data are available atBioinformaticsonline.