Principles of drug therapy for the elderly patient
Principles of drug therapy for the elderly patient
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DOI：
10.4065/78.12.1564
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发表时间：
2003-12-01
影响因子：
8.9
通讯作者：
Bahl, JJ
中科院分区：
文献类型：
--
作者：
Bressler, R;Bahl, JJ
随着美国人口老龄化，医生将治疗更多的老年患者。同时使用多种处方药治疗一种以上的疾病只是老年患者发生药物不良反应风险更大的原因之一。医生和管理人员都有责任尽可能减少这些反应的发生率。本文综述了老年人群药物不良反应风险的潜在原因，并总结了药物相互作用、代谢和分布的原则，这有助于老年患者接受适当的药物治疗。
Physicians will treat larger numbers of elderly patients as the US population ages. Being treated simultaneously for more than 1 condition with multiple prescription drugs is only 1 reason why elderly patients are at greater risk of experiencing adverse drug reactions. The need for physicians to minimize the incidence of these reactions has become incumbent on both physicians and administrators. We review the underlying reasons why the elderly population is at risk of adverse drug reactions and summarize the principles of drug-drug interaction, metabolism, and distribution, which can help elderly patients receive proper pharmacological treatment.