MECHANISMS OF TOXICOLOGICAL INTERACTIONS INVOLVING ORGANO-PHOSPHATE INSECTICIDES
MECHANISMS OF TOXICOLOGICAL INTERACTIONS INVOLVING ORGANO-PHOSPHATE INSECTICIDES
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DOI：
10.1016/0272-0590(84)90189-1
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发表时间：
1984-01-01
期刊：
影响因子：
--
通讯作者：
COHEN, SD
中科院分区：
文献类型：
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作者：
COHEN, SD
涉及有机磷杀虫剂的毒理学相互作用机制。 COHEN, S. D. (1984). 基金会。应用。毒性。 4、315-324。施用明显无毒剂量的有机磷化合物可以极大地改变其他化合物的毒性。这些可能包括其他有机磷酸酯，以及其他药物或非药物异生素。讨论了毒理学相互作用的机制。重点放在有机磷对非关键组织酯酶的抑制以及选定的含有酯和酰胺的异生物质的代谢和毒性的改变上。
Mechanisms of Toxicological Interactions Involving Organophosphate Insecticides. COHEN, S. D. (1984).Fundam. Appl. Toxicol. 4, 315–324. Administration of apparently nontoxic doses of organophosphorus compounds can greatly alter the toxicity of other compounds. These might include other organophosphates, as well as other drug or nondrug xenobiotics. Mechanisms of toxicologic interactions are discussed. Emphasis is placed upon organophosphate inhibition of noncritical tissue esterases and alterations in the metabolism and toxicity of selected ester and amide containing xenobiotics.