PKS1, a substrate phosphorylated by phytochrome that modulates light signaling in Arabidopsis
PKS1, a substrate phosphorylated by phytochrome that modulates light signaling in Arabidopsis
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DOI：
10.1126/science.284.5419.1539
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发表时间：
1999-05-28
期刊：
影响因子：
56.9
通讯作者：
Chory, J
中科院分区：
文献类型：
--
作者：
Fankhauser, C;Yeh, KC;Chory, J
植物不断地监测它们的光环境，以便最佳地生长和发育，部分是通过使用光敏色素来感知红光/远红光。光敏色素结合蛋白PKS 1（phytochrome kinase substrate 1，光敏色素激酶底物1）是光调控光敏色素激酶活性的体外底物。体内实验表明，PKS 1以光敏色素依赖的方式磷酸化并负调控光敏色素信号传导。这些数据表明，光敏色素信号由丝氨酸-苏氨酸磷酸化。
Plants constantly monitor their light environment in order to grow and develop optimally, in part through use of the phytochromes, which sense red/far-red Light. A phytochrome binding protein, PKS1 (phytochrome kinase substrate 1), was identified that is a substrate for Light-regulated phytochrome kinase activity in vitro, In vivo experiments suggest that PKS1 is phosphorylated in a phytochrome-dependent manner and negatively regulates phytochrome signaling. The data suggest that phytochromes signal by serine-threonine phosphorylation.