Absolute Configurations of Unique Harziane Diterpenes from Trichoderma Species
Absolute Configurations of Unique Harziane Diterpenes from Trichoderma Species
复制标题
木霉属独特哈齐烷二萜的绝对构型
DOI：
10.1021/ol3014717
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发表时间：
2012-08-03
期刊：
影响因子：
5.2
通讯作者：
Ji, Nai-Yun
中科院分区：
文献类型：
--
作者：
Miao, Feng-Ping;Liang, Xiao-Rui;Ji, Nai-Yun
Harzianone（2）是从长枝木霉（Trichoderma longibrachiatum）中分离得到的一个新的哈茨烷型二萜。2的结构和绝对构型通过NMR和质谱方法以及量子化学计算明确地确定。旋光度的计算支持了哈茨烷二酮（1）的绝对构型，并根据~（13）C NMR数据的比较和计算，将异哈茨烷二酮的结构修正为1。
Harzianone (2), a new harziane diterpene, was isolated from an alga-endophytic isolate of Trichoderma longibrachiatum. The structure and absolute configuration of 2 were unambiguously identified by NMR and mass spectrometric methods as well as quantum chemical calculations. The absolute configuration of harziandione (1) was supported by calculation of optical rotation, and the structure of isoharziandione was revised to 1 on the basis of C-13 NMR data comparison and calculation.