Influence of microbial infections on the progression of HIV disease

Influence of microbial infections on the progression of HIV disease
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DOI:
10.1016/s0966-842x(97)01089-5
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发表时间:
1997-08-01
影响因子:
15.9
通讯作者:
Gougeon, ML
Gougeon, ML
中科院分区:
生物学1区
文献类型:
--
作者:
Blanchard, A;Montagnier, L;Gougeon, ML

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HIV 感染与免疫激活有关,免疫激活反过来又刺激 HIV 复制。某些其他合并感染会导致免疫激活,并可能导致病毒载量增加。结核分枝杆菌等微生物合并感染的影响对于患者的生存非常重要,特别是那些感染风险高且难以获得医疗护理的患者。
HIV infection is associated with immune activation, which in turn stimulates HIV replication. Certain other co-infections cause immune activation and may contribute to an increased viral load. The impact of co-infections by microorganisms such as Mycobacterium tuberculosis can be important for patient survival, particularly those at high risk of exposure to infection and with poor access to medical care.