Surgery for metastatic tumors of the pancreas.
Surgery for metastatic tumors of the pancreas.
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DOI：
10.1186/s40792-017-0308-0
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发表时间：
2017-12
影响因子：
0.8
通讯作者：
Baba H
中科院分区：
文献类型：
--
作者：
Yagi T;Hashimoto D;Taki K;Yamamura K;Chikamoto A;Ohmuraya M;Beppu T;Baba H
胰腺转移性病变来源于其他器官并不常见。本报告的目的是评估孤立性胰腺转移瘤患者的手术结果。从2000年到2015年，9名患者在熊本大学医院消化外科接受了转移性恶性疾病的胰腺切除术。原发灶为肾癌7例，结肠癌1例，恶性黑色素瘤1例。从初次手术到胰腺切除的中位间隔时间为138个月。胰体尾切除6例，胰管切除2例，全胰切除1例。2例肾细胞癌患者和1例恶性黑色素瘤患者分别在胰腺切除术后131、108和4个月死亡。其余6例患者术后生存23.5个月。总之，胰腺转移可以在原发病灶治疗后数年发展。胰腺切除术可以获得长期生存，至少在原发性肾癌患者中是如此。
Metastatic lesion of the pancreas originated from other organs is uncommon. The aim of this report was to evaluate the outcome of surgery in patients with isolated metastases to the pancreas. Nine patients underwent pancreatic resection for metastatic malignant disease from 2000 to 2015 at the Department of Gastroenterological Surgery of the Kumamoto University Hospital. The primary lesion was renal cell carcinoma in 7 cases, colon cancer in 1 and malignant melanoma in 1. The median interval from the initial operation to pancreatic resection was 138 months. Operative procedure was distal pancreatectomy in 6 cases, pancreaticoduodenectomy in 2 and total pancreatectomy in 1. Two patients with renal cell carcinoma and 1 patient with malignant melanoma died 131, 108, and 4 months after the pancreatic resection, respectively. Other 6 patients have survived until now with 23.5 months of observation periods after pancreatic resection. In conclusion, pancreatic metastasis can develop years after the treatment of primary lesion. Pancreatic resection can achieved long-term survival, at least in the patients who had primary renal carcinoma.