Early versus late enteral feeding of mechanically ventilated patients:: Results of a clinical trial
Early versus late enteral feeding of mechanically ventilated patients:: Results of a clinical trial
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DOI：
10.1177/0148607102026003174
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发表时间：
2002-05-01
影响因子：
3.4
通讯作者：
Kollef, MH
中科院分区：
文献类型：
--
作者：
Ibrahim, EH;Mehringer, L;Kollef, MH
背景：本研究旨在比较机械通气内科患者的两种肠道喂养策略。研究方法：前瞻性对照临床试验在一所大学附属城市教学医院的重症监护室（19张病床）进行。1999年5月至2000年12月，150名患者入组。安排患者在机械通气的第1天（早期喂养组）或第5天（晚期喂养组）接受估计的每日总肠内营养需求。在机械通气的前4天，晚喂养组的患者还计划接受其估计每日肠内营养需求的20%。结果如下：75例（50%）连续合格患者入组早期喂养组，75例（50%）患者入组晚期喂养组。在机械通气的5个5天期间，总热量摄入量（2370 +/- 2000 kcal对629 575 kcal; p
Background: This study sought to compare 2 strategies for the administration of enteral feeding to mechanically ventilated medical patients. Methods: The prospective, controlled, clinical trial was carried out in a medical intensive care unit (19 beds) in a university-affiliated, urban teaching hospital. Between May 1999 and December 2000, 150 patients were enrolled. Patients were scheduled to receive their estimated total daily enteral nutritional requirements on either day 1 (early-feeding group) or day 5 (late-feeding group) of mechanical ventilation. Patients in the late-feeding group were also scheduled to receive 20% of their estimated daily enteral nutritional requirements during the first 4 days of mechanical ventilation. Results: Seventy-five (50%) consecutive eligible patients were entered into the early-feeding group and 75 (50%) patients were enrolled in the late-feeding group. During the 5 five days of mechanical ventilation, the total intake of calories (2370 +/- 2000 kcal versus 629 575 kcal; p