Platelet-to-lymphocyte ratio and C-reactive protein as markers for colorectal polyp histological type.
Platelet-to-lymphocyte ratio and C-reactive protein as markers for colorectal polyp histological type.
复制标题
血小板与淋巴细胞比值和C反应蛋白作为结直肠息肉组织学类型的标志物
DOI：
10.1186/s12885-021-08221-9
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发表时间：
2021-05-17
期刊：
影响因子：
3.8
通讯作者：
Zhang J
中科院分区：
文献类型：
--
作者：
Chen R;Wang L;Zhao Q;Li Z;Chen M;Lian G;Zhang J
背景血小板/淋巴细胞比率(PLR)和C-反应蛋白(CRP)水平是预测各种肿瘤组织学类型的指标，在此，我们评价它们在预测大肠息肉组织学类型中的价值。结果PLR和CRP值的最佳临界值分别为113.32和0.39。单因素分析显示PLR(P= 0.002)和CRP值(P= 0.009)与大肠息肉的组织学类型有关，而低PLR(P≤ 0.001)和CRP值(P= 0.017)与肿瘤最大直径(P≤ 0.001)和肿瘤个数(P= 0.0014)一起是多因素分析中的独立危险因素。
BackgroundThe platelet-to-lymphocyte ratio (PLR) and C-reactive protein (CRP) level are markers that have been reported to predict the histological type of various tumors, and here, we evaluated their utility in predicting colorectal polyp histological types.MethodsWe retrospectively reviewed 172 patients with colorectal polyps who underwent endoscopic polypectomy. The associations between histological type and clinicopathologic parameters were assessed by multivariate analysis.ResultsThe optimal PLR and CRP cut-off values were 113.32 and 0.39, respectively. The PLR (P= 0.002) and CRP (P= 0.009) values were associated with the histological type according to the univariate analysis, whereas low PLR (P≤ 0.001) and CRP (P= 0.017) values were independent risk factors in the multivariate analysis together with maximum tumor diameter (P≤ 0.001) and tumor number (P= 0.0014).ConclusionsPreoperative PLR and CRP are correlated with the colorectal polyp histological type.
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影响因子：
3.7
作者：
Takagi S;Sato S;Oh-hara T;Takami M;Koike S;Mishima Y;Hatake K;Fujita N
通讯作者：
Fujita N
影响因子：
0.6
作者：
Constantin, Georgiana Bianca;Firescu, Dorel;Constantinoiu, Silviu
通讯作者：
Constantinoiu, Silviu
影响因子：
5.6
作者：
DIRSCHMID, K;KIESLER, J;SCHOBEL, B
通讯作者：
SCHOBEL, B
影响因子：
5.3
作者：
Tanaka, Shinji;Kashida, Hiroshi;Tajiri, Hisao
通讯作者：
Tajiri, Hisao
影响因子：
6.3
作者：
Tanaka, Shinji;Saitoh, Yusuke;Shimosegawa, Tooru
通讯作者：
Shimosegawa, Tooru