Bone healing around titanium and titanium nitride-coated dental implants with three surfaces: an experimental study in rats.
Bone healing around titanium and titanium nitride-coated dental implants with three surfaces: an experimental study in rats.
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具有三个表面的钛和氮化钛涂层牙种植体周围的骨愈合：大鼠实验研究。
DOI：
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发表时间：
2003
影响因子：
3.6
通讯作者：
A. Piattelli
中科院分区：
文献类型：
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作者：
A. Scarano;M. Piattelli;G. Vrespa;G. Petrone;G. Iezzi;A. Piattelli
背景
氮化钛（TiN）已在许多领域用作手术器械的涂层，目的是创造更耐磨损和耐腐蚀的材料，并减少粘附。
目的
本研究的目的是评估 TiN 涂层牙种植体的生物相容性。
材料和方法
本研究使用了四十五只大鼠。使用了 180 个 2 mm x 2 mm 种植体（P.H.I. San Vittore Olona，米兰，意大利）。将植入物分为以下三组： 第 1 组（n = 60）：30 个机加工和 30 个机加工涂层第 2 组（n = 60）：30 个喷砂和 30 个喷砂涂层第 3 组（n = 60）：30 个等离子喷涂钛、30 个等离子喷涂钛并涂有 TiN 每只大鼠体内放置四个植入物，两个植入物在右侧胫骨上涂有 TiN，另外两个植入物在右侧胫骨上涂有 TiN。左侧为未涂层的植入物。 5、10、20、30或60天后处死动物。另外 18 个种植体用于表面粗糙度分析。
结果
本研究表明，TiN 涂层种植体周围的愈合情况与未涂层表面周围观察到的情况相似。
结论
TiN涂层表现出良好的生物相容性，不会对种植体周围骨的形成产生不良影响，并且不会改变表面粗糙度值。
BACKGROUND
Titanium nitride (TiN) has been used in many fields as a coating of surgical instruments, with the purpose of creating materials more resistant to wear and corrosion and also reducing adhesion.
PURPOSE
The aim of this study was to evaluate the biocompatibility of TiN-coated dental implants.
MATERIALS AND METHODS
Forty-five rats were used in this study. One hundred eighty 2 mm x 2 mm implants (P.H.I. San Vittore Olona, Milano, Italy) were used. The implants were divided into the following three groups: Group 1 (n = 60): 30 machined and 30 machined coated with Group 2 (n = 60): 30 sandblasted and 30 sandblasted coated with Group 3 (n = 60): 30 titanium plasma sprayed, 30 titanium plasma sprayed and coated with TiN Four implants were placed in each rat, two implants coated with TiN on the right tibia and two uncoated implants on the left. The animals were killed after 5, 10, 20, 30, or 60 days. Another 18 implants were used for surface roughness analysis.
RESULTS
The present study showed that the healing around the TiN-coated implants was similar to that observed around the uncoated surfaces.
CONCLUSIONS
TiN coating demonstrated a good biocompatibility, did not have untoward effects on the periimplant bone formation, and did not change the surface roughness values.