Accuracy of GFR predictive equations in renal transplantation: Validation of a new turbidimetric cystatin C assay on Architect c8000®
Accuracy of GFR predictive equations in renal transplantation: Validation of a new turbidimetric cystatin C assay on Architect c8000®
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DOI：
10.1016/j.clinbiochem.2011.10.018
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发表时间：
2012-01-01
影响因子：
2.8
通讯作者：
Cristol, J. P.
中科院分区：
文献类型：
--
作者：
Bargnoux, A. S.;Servel, A. C.;Cristol, J. P.
目的：在Architect c8000（R）分析仪上评价Sentinel-PETIA半胱氨酸蛋白酶抑制剂C。设计和方法：我们通过与肾移植受者的参考同位素方法进行比较来评估分析性能和临床相关性。结果：该测定法具有可靠的精密度，接近非标准化Siemens-PENIA方法。结论：Cystatin C在60 mL/min/1.73 m（2）的临界水平改善了GFR测定。IFCC标准化后可能需要新的公式。(C)2011年加拿大临床化学家协会。爱思唯尔公司出版All rights reserved.
Objectives: To evaluate the Sentinel-PETIA cystatin C on Architect c8000 (R) analyzer.Design and methods: We assessed analytical performances and clinical relevance by comparison with a reference isotopic method in kidney transplant recipients.Results: This assay exhibited reliable precision and was close to the non standardized Siemens-PENIA method. All tested equations allowed reliable assessment of GFR.Conclusions: Cystatin C improved GFR determination at the critical level of 60 mL/min/1.73 m(2). New formulas might be necessary after IFCC standardization. (C) 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.