Clinical characteristics and outcomes of in-hospital cardiac arrest among patients with and without COVID-19.
Clinical characteristics and outcomes of in-hospital cardiac arrest among patients with and without COVID-19.
复制标题
有或没有COVID-19的患者中院内心脏骤停的临床特征和结果。
DOI：
10.1016/j.resplu.2020.100054
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发表时间：
2020-12
影响因子：
2.4
通讯作者：
Horowitz JM
中科院分区：
文献类型：
--
作者：
Yuriditsky E;Mitchell OJL;Brosnahan SB;Smilowitz NR;Drus KW;Gonzales AM;Xia Y;Parnia S;Horowitz JM
旨在确定患有院内心脏骤停 (IHCA) 的 COVID-19 患者与未患 COVID-19 的患者的结局。我们对 IHCA 病例进行了单中心回顾性研究。将患有 COVID-19 的患者与前一年连续未患过 COVID-19 的患者进行比较。评估了自主循环恢复 (ROSC)、30 天生存率和 30 天脑功能类别 (CPC)。确定了 55 名患有 IHCA 的 COVID-19 患者，并与 2019 年连续 55 名 IHCA 患者进行了比较。COVID-19 队列更有可能需要血管活性药物（67.3% vs 32.7%，p = 0.001）、有创机械通气（76.4% vs 23.6%，p < 0.001）、肾脏替代治疗（18.2% vs 3.6%，p = 0.029）和重症监护室护理（83.6% vs 50.9%，p = 0.001）在 IHCA 之前。 COVID-19 患者的心肺复苏持续时间较短（10 分钟与 22 分钟，p = 0.002）。 ROSC（38.2% vs 49.1%，p = 0.336）和 30 天生存率（20% vs 32.7%，p = 0.194）没有差异。 30 天脑功能类别 1 或 2 在非 COVID 患者中更为常见（27.3% vs 9.1%，p = 0.048）。患有和不患有 COVID-19 的 IHCA 患者的自主循环恢复和 30 天生存率相似。与之前发布的数据相比，我们报告了在 COVID-19 中进行 IHCA 后的 ROSC 和 30 天生存率更高。
To define outcomes of patients with COVID-19 compared to patients without COVID-19 suffering in-hospital cardiac arrest (IHCA). We performed a single-center retrospective study of IHCA cases. Patients with COVID-19 were compared to consecutive patients without COVID-19 from the prior year. Return of spontaneous circulation (ROSC), 30-day survival, and cerebral performance category (CPC) at 30-days were assessed. Fifty-five patients with COVID-19 suffering IHCA were identified and compared to 55 consecutive IHCA patients in 2019. The COVID-19 cohort was more likely to require vasoactive agents (67.3% v 32.7%, p = 0.001), invasive mechanical ventilation (76.4% v 23.6%, p < 0.001), renal replacement therapy (18.2% v 3.6%, p = 0.029) and intensive care unit care (83.6% v 50.9%, p = 0.001) prior to IHCA. Patients with COVID-19 had shorter CPR duration (10 min v 22 min, p = 0.002). ROSC (38.2% v 49.1%, p = 0.336) and 30-day survival (20% v 32.7%, p = 0.194) did not differ. A 30-day cerebral performance category of 1 or 2 was more common among non-COVID patients (27.3% v 9.1%, p = 0.048). Return of spontaneous circulation and 30-day survival were similar between IHCA patients with and without COVID-19. Compared to previously published data, we report greater ROSC and 30-day survival after IHCA in COVID-19.
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DOI：
10.1136/bmj.m3513
发表时间：
2020-09-30
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Hayek SS;Brenner SK;Azam TU;Shadid HR;Anderson E;Berlin H;Pan M;Meloche C;Feroz R;O'Hayer P;Kaakati R;Bitar A;Padalia K;Perry D;Blakely P;Gupta S;Shaefi S;Srivastava A;Charytan DM;Bansal A;Mallappallil M;Melamed ML;Shehata AM;Sunderram J;Mathews KS;Sutherland AK;Nallamothu BK;Leaf DE;STOP-COVID Investigators
通讯作者：
STOP-COVID Investigators
DOI：
10.1001/jama.2020.6775
发表时间：
2020-01-01
期刊：
JAMA, Journal of the American Medical Association
影响因子：
--
作者：
Richardson, Safiya;Hirsch, Jamie S.;,
通讯作者：
,
影响因子：
37.8
作者：
Edelson, Dana P.;Sasson, Comilla;Topjian, Alexis A.
通讯作者：
Topjian, Alexis A.
影响因子：
168.9
作者：
Cummings, Matthew J.;Baldwin, Matthew R.;O'Donnell, Max R.
通讯作者：
O'Donnell, Max R.
影响因子：
8.8
作者：
Meaney, Peter A.;Nadkarni, Vinay M.;Berg, Robert A.
通讯作者：
Berg, Robert A.