Design of Polymeric Carriers for Cancer-Specific Gene Targeting: Utilization of Abnormal Protein Kinase Cα Activation in Cancer Cells
Design of Polymeric Carriers for Cancer-Specific Gene Targeting: Utilization of Abnormal Protein Kinase Cα Activation in Cancer Cells
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DOI：
10.1021/ja805364s
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发表时间：
2008-11-12
影响因子：
15
通讯作者：
Katayama, Yoshiki
中科院分区：
文献类型：
--
作者：
Kang, Jeong-Hun;Asai, Daisuke;Katayama, Yoshiki
我们成功地在癌细胞特异性基因表达通过使用响应蛋白激酶C α，这是在各种类型的癌细胞中激活的复合体。
We succeeded in cancer cell specific gene expression by using a polyplex responsive to protein kinase C alpha, which is activated in various types of cancer cells.