Lipidomics: New Tools and Applications
Lipidomics: New Tools and Applications
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DOI：
10.1016/j.cell.2010.11.033
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发表时间：
2010-12-10
期刊：
影响因子：
64.5
通讯作者：
Wenk, Markus R.
中科院分区：
文献类型：
--
作者：
Wenk, Markus R.
曾经被简单地视为碳储存储存库的脂质，在生物系统的戏剧中不再被视为旁观者。脂类组学的新兴领域是由技术推动的，尤其是质谱学，但也受到活细胞中脂类及其生物合成酶的检测和表征的补充方法的推动。这些集成工具的开发有望极大地促进我们对脂类的不同生物学作用的理解。
Once viewed simply as a reservoir for carbon storage, lipids are no longer cast as bystanders in the drama of biological systems. The emerging field of lipidomics is driven by technology, most notably mass spectrometry, but also by complementary approaches for the detection and characterization of lipids and their biosynthetic enzymes in living cells. The development of these integrated tools promises to greatly advance our understanding of the diverse biological roles of lipids.