Prolonged QTc interval predicts mortality in patients with Type 1 diabetes mellitus
Prolonged QTc interval predicts mortality in patients with Type 1 diabetes mellitus
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DOI：
10.1046/j.1464-5491.2001.00446.x
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发表时间：
2001-03-01
影响因子：
3.5
通讯作者：
Parving, HH
中科院分区：
文献类型：
--
作者：
Rossing, P;Breum, L;Parving, HH
目的评估QTc间期延长和QT离散度作为1型糖尿病患者校正明确危险因素后全因死亡率和心血管死亡率的预测因素。方法从一个队列中所有成年1型糖尿病患者，糖尿病病程大于或等于5年，在1984年就诊，并在一项观察性研究中随访10年（n = 939），确定了具有静息基线心电图的所有受试者（n = 697，360名男性）。测量QT间期并校正心率（QTc）。结果431例患者基线时白蛋白尿正常，
Aims To evaluate prolonged QTc interval and QT dispersion as predictors of all-cause and cardiovascular mortality after adjustment for well-established risk factors in Type 1 diabetic patients.Methods From a cohort of all adult Type 1 diabetic patients, duration of diabetes greater than or equal to5 years, attending the clinic in 1984 and followed in an observational study for 10 years (n = 939), all subjects with resting baseline electrocardiograms were identified (n = 697, 360 males). The QT length was measured and corrected for heart rate (QTc). Maximal QTc length (QTc max) and QT dispersion were determined.Results At baseline, 431 had normoalbuminuria (