ANTIBIOTICS FROM GLIDING BACTERIA .33. THE AURACHINS, NEW QUINOLINE ANTIBIOTICS FROM MYXOBACTERIA - PRODUCTION, PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES
ANTIBIOTICS FROM GLIDING BACTERIA .33. THE AURACHINS, NEW QUINOLINE ANTIBIOTICS FROM MYXOBACTERIA - PRODUCTION, PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES
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DOI：
10.7164/antibiotics.40.258
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发表时间：
1987-03-01
影响因子：
3.3
通讯作者：
REICHENBACH, H
中科院分区：
文献类型：
--
作者：
KUNZE, B;HOFLE, G;REICHENBACH, H
用丙酮从粘细菌Stigmatella aurantiaca Sg a15菌株的生物质中提取并经柱层析纯化了一种新的喹啉类生物碱-奥瑞钦。所描述的四种aurachin A、B、C和D对革兰氏阳性菌和少数酵母菌和霉菌具有抑制作用。他们阻断了牛心亚线粒体颗粒中的NADH氧化。
The aurachins, new quinoline alkaloids, were extracted with acetone from the biomass of the myxobacterium, Stigmatella aurantiaca strain Sg a15 and purified by column chromatography. The four described aurachins A, B, C and D, were inhibitory for Gram-positive bacteria and a few yeasts and molds. They blocked NADH oxidation in beef heart submitochondrial particles.