Clinical Features of Patients With Ebola Virus Disease in Sierra Leone
Clinical Features of Patients With Ebola Virus Disease in Sierra Leone
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DOI：
10.1093/cid/civ319
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发表时间：
2015-08-15
影响因子：
11.8
通讯作者：
Zhong, Yanwei
中科院分区：
文献类型：
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作者：
Qin, Enqiang;Bi, Jingfeng;Zhong, Yanwei
背景关于埃博拉病毒病（EVD）患者的临床和实验室数据仍然非常有限。总结EVD患者的临床特点，分析其死亡相关因素。2014年10月1日至11月14日期间在弗里敦中国-塞拉利昂友谊医院接受治疗的患者入组本研究。回顾性分析20例患者的临床资料。61例患者被证实患有EVD;其中28例（45.9%）为男性，33例（54.1%）为女性。他们的中位年龄为28岁（范围，1.17-67岁）。从症状发作到门诊访视时间的中位持续时间为5天（范围，1-16天）。死亡42例（68.9%）。在确诊病例中，18.0%没有出现发热。年龄>30岁的患者的病死率高于年龄> 30岁的患者。
Background. Clinical and laboratory data available on patients with Ebola virus disease (EVD) remain extremely limited. We summarized the clinical characteristics of patients with EVD and analyzed the factors related to their death.Methods. Patients admitted for care at the Freetown China-Sierra Leone Friendship Hospital during 1 October-14 November 2014 were enrolled in this study. The clinical data of these patients were retrospectively analyzed.Results. Sixty-one patients were confirmed to have EVD; 28 of them (45.9%) were male and 33 (54.1%) were female. Their median age was 28 years (range, 1.17-67 years). The median duration from symptom onset to clinic visit time was 5 days (range, 1-16 days). Among these patients, 42 of them (68.9%) died. Of the confirmed cases, 18.0% did not present with fever. Patients aged >30 years had a higher fatality rate than those