Diabetes distress is more strongly associated with HbA1c than depressive symptoms in adolescents with type 1 diabetes: Results from Diabetes MILES Youth-Australia
Diabetes distress is more strongly associated with HbA1c than depressive symptoms in adolescents with type 1 diabetes: Results from Diabetes MILES Youth-Australia
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DOI：
10.1111/pedi.12641
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发表时间：
2018-06-01
影响因子：
3.4
通讯作者：
Speight, Jane
中科院分区：
文献类型：
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作者：
Hagger, Virginia;Hendrieckx, Christel;Speight, Jane
背景：糖化血红蛋白(HbA1c)在青春期比其他生命阶段都要高。在青少年中的一些研究表明，抑郁症状与HbA1c不佳有关。目的：确定抑郁症状和糖尿病痛苦的相对贡献，以解释1型糖尿病青少年中HbA1c的差异。参与者和方法：DM Miles青年研究受试者完成了评估抑郁症状(青少年患者健康问卷：PHQA-8)、糖尿病痛苦(青少年问题领域：付费-T)和自我报告的社会人口学和临床变量的问卷，包括他们最近的HbA1c。结果：450例受试者年龄(平均+/-SD)为15.7±-1.9岁，糖尿病病程为6.9+/-4.3年，男性占38%(n=169)。21%(n=96)经历了中到重度的抑郁症状(PHQA-8>；=11)，36%(n=162)经历了高度糖尿病痛苦(Payed-T>；90)。在最终的回归模型中，HbA1c的解释为：糖尿病病程(β=0.14，P=.001)、自我血糖监测(β=-0.20，P
Background: Glycated hemoglobin (HbA1c) is higher during adolescence than at any other life stage. Some research among adolescents indicates that depressive symptoms are associated with suboptimal HbA1c. However, research among adults suggests diabetes distress is a stronger predictor of HbA1c than depressive symptoms.Objective: To determine the relative contributions of depressive symptoms and diabetes distress to explain the variance in HbA1c among adolescents with type 1 diabetes.Participants and methods: Diabetes MILES Youth Study respondents aged 13 to 19 years completed questionnaires assessing depressive symptoms (Patient Health Questionnaire for Adolescents: PHQA-8), diabetes distress (Problem Areas in Diabetes-Teen version: PAID-T), and self-reported socio-demographic and clinical variables, including their most recent HbA1c. Stepwise hierarchical multiple regression was conducted to examine the contributions of depressive symptoms and diabetes distress to HbA1c.Results: Participants (N=450) had a (mean +/- SD) age of 15.7 +/- 1.9 years; diabetes duration of 6.9 +/- 4.3 years; and 38% (n=169) were male. Twenty-one percent (n=96) experienced moderate-to-severe depressive symptoms (PHQA-8 >= 11) and 36% (n=162) experienced high diabetes distress (PAID-T>90). In the final regression model, HbA1c was explained by: diabetes duration (beta =.14, P=.001), self-monitoring of blood glucose (beta=-.20, P