Direct measurement of human sympathetic nerve conduction velocity
Direct measurement of human sympathetic nerve conduction velocity
复制标题
DOI：
10.1002/mus.10490
复制
发表时间：
2004-01-01
期刊：
影响因子：
3.4
通讯作者：
Kuzuhara, S
中科院分区：
文献类型：
--
作者：
Kondo, M;Iwase, S;Kuzuhara, S
我们评估了一种直接测量人类交感神经传导速度（CV）的方法，使用皮肤交感神经活动（SSNA）的双记录方法，通过显微神经摄影术。同时记录腘窝近端和远端部位（短距离研究）或腘窝和踝关节（长距离研究）胫神经中的SSNA。在这两项研究中，CV通过将皮肤上的电极间距离除以上升相（上升相分析）或积分爆发峰值（峰-峰分析）之间的传导时间差来确定。使用长距离和峰-峰分析的测量具有最高的准确度;它是一种顺向传导测量，与诱发刺激无关，具有高时间分辨率，并且不受效应器官状况的影响。静息SSNA的平均CV为0.93 +/- 0.09 m/s。
We evaluated a method for direct measurement of conduction velocity (CV) in sympathetic nerves in humans using a double-recording method of skin sympathetic nerve activity (SSNA) by microneurography. SSNA in the tibial nerve was recorded simultaneously at proximal and distal sites in the popliteal fossa (short-distance study) or at the popliteal fossa and ankle (long-distance study). In both studies, CVs were determined by dividing the interelectrode distance on the skin by the difference in conduction time between the rising-phases (rising-phase analysis) or peaks of the integrated bursts (peak-to-peak analysis). The measurement using long distance and peak-to-peak analysis had the highest accuracy; it is an orthodromic conduction measurement, is unrelated to eliciting stimulus, has high temporal resolution, and is not affected by the effector organ conditions. The average CV of resting SSNA was 0.93 +/- 0.09 m/s.