Effect of Urbanization on Neospora caninum Seroprevalence in White-Tailed Deer (Odocoileus virginianus)
Effect of Urbanization on Neospora caninum Seroprevalence in White-Tailed Deer (Odocoileus virginianus)
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DOI：
10.1007/s10393-018-1390-x
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发表时间：
2019-03-01
期刊：
影响因子：
2.5
通讯作者：
Dennis, Patricia M.
中科院分区：
文献类型：
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作者：
Ballash, Gregory A.;Jenkins, Mark C.;Dennis, Patricia M.
原生动物犬新孢子虫在家养动物和野生动物之间传播。城市化环境和鹿密度可能促进这种传播，并在N的溢出中发挥关键作用。从家养动物到野生动物。白尾鹿（Odocoileus virginianus; WTD）是维持N.犬在美国。在这里，我们分析了来自美国俄亥俄州从郊区到城市梯度的自然保护区的444个WTD的血清样品。抗N.用重组NcGRA 6 ELISA法检测，阳性率为23.6%（105/444）。血清阳性的重要危险因素是年龄和城市化。来自城市化环境的鹿比来自郊区栖息地的鹿（16/121，13.2%）血清阳性的几率更大（89/323，27.6%），并且当调整年龄和性别时，这种差异仍然存在。年龄也是一个重要的风险因素，成年人比小鹿和一岁鸽更容易出现血清阳性。我们推测WTD的主要暴露途径是摄入N。来自污染环境和城市化栖息地的犬卵囊促进了这种接触。
The protozoan Neospora caninum is transmitted between domestic and wildlife species. Urbanized environments and deer density may facilitate this transmission and play a critical role in the spillover of N. caninum from domestic animals to wildlife. White-tailed deer (Odocoileus virginianus; WTD) are an important intermediate host for maintaining the sylvatic cycle of N. caninum in the USA. Here, we assayed serum samples from 444 WTD from a nature reservation across a suburban to urban gradient in Ohio, USA. Antibodies to N. caninum were found by using a recombinant NcGRA6 ELISA in 23.6% (105/444). Significant risk factors for seropositivity were age class and urbanization. Deer from urbanized environments were at greater odds of being seropositive (89/323, 27.6%) than those from suburban habitats (16/121, 13.2%), and this difference persisted when adjusting for age and sex. Age was also a significant risk factor with adults at greater odds to be seropositive than fawns and yearlings. We speculate the main route of exposure in WTD is ingestion of N. caninum oocysts from contaminated environments and urbanized habitats facilitate this exposure.