How often does squamous cell carcinoma of the skin metastasize?

How often does squamous cell carcinoma of the skin metastasize?
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皮肤鳞状细胞癌多久转移一次?

DOI:
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发表时间:
1965
影响因子:
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通讯作者:
H. Z. Lund
H. Z. Lund
中科院分区:
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文献类型:
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作者:
H. Z. Lund

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常见的鳞状细胞癌转移发生在太阳损伤的皮肤是罕见的。绝大多数人似乎只在当地具有侵略性。转移更可能来自与其他先前病变(烧伤、疤痕、慢性溃疡、砷性皮肤病、x射线损伤)或病因不明的癌症。危险病变的其他特征是体积大、细胞密度大、弥漫性浸润。在其他条件相同的情况下,间变性肿瘤可能比分化良好的肿瘤更容易转移,转移范围也更广。
Metastasis from the common squamous cell carcinoma arising in sun-damaged skin is rare. A vast majority appear to be only locally aggressive. Metastasis is more likely from carcinomas related to other antecedent lesions (burns, scars, chronic ulcers, arsenical dermatosis, x-ray injury) or of unknown etiology. Other characteristics of a dangerous lesion are large size great cellularity, and diffuse invasion. Other things being equal, the anaplastic tumor is probably more likely to metastasize and to metastasize more widely than the well-differentiated tumor.