Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology

Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology
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DOI:
10.1111/epi.13670
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发表时间:
2017-04-01
期刊:
影响因子:
5.6
通讯作者:
Zuberi, Sameer M.
Zuberi, Sameer M.
中科院分区:
医学1区
文献类型:
--
作者:
Fisher, Robert S.;Cross, J. Helen;Zuberi, Sameer M.

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国际抗癫痫联盟(ILAE)提出了经修订的癫痫发作类型的业务分类。这一修订的目的是认识到一些癫痫发作类型既可以是局灶性发作,也可以是全身性发作,允许在没有观察到发作时进行分类,包括一些缺失的癫痫类型,并采用更透明的名称。由于目前的知识不足以形成以科学为基础的分类,2017年的分类是可操作的(实用的),并且是以1981年的分类为基础的,该分类于2010年扩展。改变包括:(1)局灶性发作;(2)意识作为局灶性发作的分类器;(3)消除了难治性、简单部分性、复杂性部分性、精神性和继发性泛发性发作;(4)新的局灶性发作类型包括自律性、行为停止、多动症、自主神经、认知和情绪;(5)无张力、阵挛、癫痫痉挛、肌阵挛和强直性发作可以是局灶性或全身性发作;(6)局灶性到双侧强直-阵挛发作取代了继发性全身性发作;(7)新的全身性发作类型为失神伴眼睑肌阵挛、肌阵挛消失、肌阵挛-紧张性发作、肌阵挛-紧张性阵挛;(8)起病不明的癫痫发作可能有仍可分类的特征。新的分类并不代表根本的变化,但允许在命名癫痫类型方面有更大的灵活性和透明度。
The International League Against Epilepsy (ILAE) presents a revised operational classification of seizure types. The purpose of such a revision is to recognize that some seizure types can have either a focal or generalized onset, to allow classification when the onset is unobserved, to include some missing seizure types, and to adopt more transparent names. Because current knowledge is insufficient to form a scientifically based classification, the 2017 Classification is operational (practical) and based on the 1981 Classification, extended in 2010. Changes include the following: (1) partial becomes focal; (2) awareness is used as a classifier of focal seizures; (3) the terms dyscognitive, simple partial, complex partial, psychic, and secondarily generalized are eliminated; (4) new focal seizure types include automatisms, behavior arrest, hyperkinetic, autonomic, cognitive, and emotional; (5) atonic, clonic, epileptic spasms, myoclonic, and tonic seizures can be of either focal or generalized onset; (6) focal to bilateral tonic-clonic seizure replaces secondarily generalized seizure; (7) new generalized seizure types are absence with eyelid myoclonia, myoclonic absence, myoclonic-atonic, myoclonic-tonic-clonic; and (8) seizures of unknown onset may have features that can still be classified. The new classification does not represent a fundamental change, but allows greater flexibility and transparency in naming seizure types.