Association between anterior bone loss and anterior heterotopic ossification in hybrid surgery.
Association between anterior bone loss and anterior heterotopic ossification in hybrid surgery.
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混合手术中前路骨丢失与前路异位骨化之间的关联
DOI：
10.1186/s12891-020-03664-w
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发表时间：
2020-10-08
影响因子：
2.3
通讯作者：
Wang B
中科院分区：
文献类型：
--
作者：
He J;Liu H;Wu T;Ding C;Huang K;Hong Y;Wang B
混合手术（HS）已成为治疗多节段颈椎退行性椎间盘疾病的替代手术，并取得了令人满意的结果。然而，最近出现了一些不良后果，例如异位骨化（HO）和前骨丢失（ABL）。此外，HO主要位于颈椎间盘间隙的后侧和外侧。前异位骨化（AHO）形成的机制可能不同，其与ABL的关系尚不确定。对 2010 年 12 月至 2017 年 12 月期间接受连续两级 HS 并至少随访 2 年的 97 名患者的影像学和临床结果进行了分析。对术后 X 线照片进行评估并与最初的术后胶片进行比较，以确定 ABL 和 AHO 的发生率。 ABL的总体发生率为44.3%（43/97）。 70.6% 的 AHO 病例（33.3% 轻度、41.7% 中度、25.0% 重度）和 38.8% 的非 AHO 病例（38.7% 轻度、45.2% 中度、16.1% 重度）被发现。发现 ABL 和 AHO 发生之间存在显着相关性 (P = 0.016)。 AHO组与非AHO组假体-终板深度比或椎间盘间隙角度变化无显着差异（P > 0.05）。与术前相比，AHO组和非AHO组术后临床结局评分均显着改善，但两组间差异无统计学意义（P >0.05）。 ABL多见于HS，且与AHO有关。 AHO 的形成可能是术后骨重建以及 ABL 的一个组成部分。
Hybrid surgery (HS) has become an alternative procedure for the treatment of multilevel cervical degenerative disc disease with satisfactory outcomes. However, some adverse outcomes have recently emerged, such as heterotopic ossification (HO) and anterior bone loss (ABL). Furthermore, HO was found mostly located in the posterior and lateral of the cervical intervertebral disc space. The mechanism of anterior heterotopic ossification (AHO) formation may be different, and its relationship with ABL was uncertain. Radiographical and clinical outcomes of ninety-seven patients who had undergone contiguous two-level HS between December 2010 and December 2017 and with a minimum of 2-year follow-up were analyzed. Postoperative radiographs were evaluated and compared to the initial postoperative films to determine the incidence of ABL and AHO. The overall incidence rate of ABL was 44.3% (43/97). It was identified in 70.6% of AHO cases (33.3% mild, 41.7% moderate, 25.0% severe) and 38.8% of non-AHO cases (38.7% mild, 45.2% moderate, 16.1% severe). A significant association between ABL and AHO occurrence was found (P = 0.016). There was no significant difference in prosthesis–endplate depth ratio or disc space angle change between the AHO group and the non-AHO group (P > 0.05). Compared with data preoperatively, clinical outcome scores significantly improved after surgery in both the AHO and non-AHO groups, with no significant differences between the two groups (P > 0.05). ABL was common in HS, and it related to AHO. The formation of AHO could be an integral part of postoperative bone remodeling, as well as ABL.
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影响因子：
1
作者：
Park JB;Chang H;Yeom JS;Suk KS;Lee DH;Lee JC
通讯作者：
Lee JC
影响因子：
3
作者：
Shin, Dong Ah;Yi, Seong;Shin, Hyun Cheol
通讯作者：
Shin, Hyun Cheol
影响因子：
3
作者：
Tumialan, Luis. M.;Gluf, Wayne M.
通讯作者：
Gluf, Wayne M.
影响因子：
2.8
作者：
Kim, Sang Hyun;Chung, Young Sun;Han, In Bo
通讯作者：
Han, In Bo
影响因子：
2.3
作者：
Kieser DC;Cawley DT;Fujishiro T;Tavolaro C;Mazas S;Boissiere L;Obeid I;Pointillart V;Vital JM;Gille O
通讯作者：
Gille O