Electrospray Ionization Mass Spectrometry of Intrinsically Cationized Nanoparticles, [Au144/146(SC11H22N(CH2CH3)3+)x(S(CH2)5CH3)y]x+
Electrospray Ionization Mass Spectrometry of Intrinsically Cationized Nanoparticles, [Au144/146(SC11H22N(CH2CH3)3+)x(S(CH2)5CH3)y]x+
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DOI：
10.1021/ja906976w
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发表时间：
2009-11-11
影响因子：
15
通讯作者：
Murray, Royce W.
中科院分区：
文献类型：
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作者：
Fields-Zinna, Christina A.;Sardar, Rajesh;Murray, Royce W.
钙的电喷雾三重四极杆质谱。1.6 nm直径的硫醇盐保护的金纳米粒子已经实现了比以前的报告中更高的分辨率。结果揭示了具有式Au 144 L 60和Au 146 L59的纳米颗粒的存在，其作为混合物存在于样品中。改进的分离度是基于通过将多个[-SC 11 H22 N（CH 2CH 3）（3）（+）]配体交换到原始[-S（CH 2）（5）CH 3]配体壳层中来降低m/z。因此，纳米颗粒本质上是阳离子化的，并表现为一系列10+至15+质谱峰。通过碰撞诱导解离测量确认了分配的电荷状态。
Electrospray ionization triple-quadrupole mass spectrometry of ca. 1.6 nm diameter thiolate-protected gold nanoparticles has been achieved at higher resolution than in previous reports. The results reveal the presence of nanoparticles with formulas Au144L60 and Au146L59, present in the sample as a mixture. The improved resolution is based on lowering m/z by exchanging multiple [-SC11H22N(CH2CH3)(3)(+)] ligands into the original [-S(CH2)(5)CH3] ligand shell. The nanoparticles are thus intrinsically cationized and appear as a series of 10+ to 15+ mass spectral peaks. The assigned state of charge was confirmed by a collision-induced dissociation measurement.