Clinical features of pediatric patients with COVID-19: a report of two family cluster cases

Clinical features of pediatric patients with COVID-19: a report of two family cluster cases
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DOI:
10.1007/s12519-020-00356-2
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发表时间:
2020-03-16
影响因子:
8.7
通讯作者:
Jiang, Rong-Meng
Jiang, Rong-Meng
中科院分区:
医学1区
文献类型:
--
作者:
Ji, Li-Na;Chao, Shuang;Jiang, Rong-Meng

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背景2019冠状病毒病(COVID-19)在地球仪迅速蔓延。所有年龄段的人都容易感染COVID-19。然而,关于儿科患者的文献报道有限。方法为提高对COVID-19感染儿童的认识,我们回顾性分析了来自两个家庭聚集性的2例确诊的儿童病例。描述了患儿及其家属的临床特点和实验室检查结果。结果2例患儿均表现为轻微的呼吸道或消化道症状。两人胸部CT均正常。经过一般和对症治疗,两个孩子都很快康复。两个家庭都有到湖北省旅行的历史。结论COVID-19患儿多为家族聚集性或有密切接触史。受感染儿童的临床症状比受感染成人轻。对感染儿童要重视早识别、早诊断、早治疗。
Background Coronovirus disease 2019 (COVID-19) has spread rapidly across the globe. People of all ages are susceptible to COVID-19. However, literature reports on pediatric patients are limited. Methods To improve the recognition of COVID-19 infection in children, we retrospectively reviewed two confirmed pediatric cases from two family clusters. Both clinical features and laboratory examination results of the children and their family members were described. Results The two confirmed children only presented with mild respiratory or gastrointestinal symptoms. Both of them had normal chest CT images. After general and symptomatic treatments, both children recovered quickly. Both families had travel histories to Hubei Province. Conclusions Pediatric patients with COVID-19 are mostly owing to family cluster or with a close contact history. Infected children have relatively milder clinical symptoms than infected adults. We should attach importance to early recognition, early diagnosis, and early treatment of infected children.