Severity and impairment of allergic rhinitis in patients consulting in primary care
Severity and impairment of allergic rhinitis in patients consulting in primary care
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DOI：
10.1016/j.jaci.2005.09.047
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发表时间：
2006-01-01
影响因子：
14.2
通讯作者：
Allaf, B
中科院分区：
文献类型：
--
作者：
Bousquet, J;Neukirch, F;Allaf, B
背景：变应性鼻炎是一种影响生活、睡眠和工作质量的疾病。最近提出了一种新的变应性鼻炎分类——过敏性鼻炎及其影响哮喘（ARIA）。目的：研究变应性鼻炎的影响，应用ARIA定义来确定变应性鼻炎的严重程度和病程。方法：对全科就诊的3052例变应性鼻炎患者进行分析。根据ARIA的4个级别对患者进行分类。对所有患者的生活质量（鼻结膜炎生活质量问卷）、睡眠（Jenkins问卷）和工作表现（过敏特异性工作效率和活动障碍问卷）进行评估。结果：轻度间断性鼻炎占11%，轻度持续性鼻炎占8%，中度/重度间断性鼻炎占35%，中度/重度持续性鼻炎占46%。鼻炎的严重程度对生活质量、睡眠、日常活动和工作表现的影响比鼻炎的持续时间更大。在中度/重度鼻炎中，超过80%的患者报告活动受损，而轻度鼻炎患者只有40%。结论：“中度/重度”应改为“重度”。然而，有必要对普通人群进行研究，以评估4类ARIA变应性鼻炎的患病率，特别是那些没有向医生咨询症状的患者。
Background: Allergic rhinitis is a disease impairing quality of life, sleep, and work. A new classification for allergic rhinitis, Allergic Rhinitis and its Impact on Asthma (ARIA), has recently been proposed.Objective: To study the effect of allergic rhinitis using ARIA definitions to determine severity and duration.Methods: A total of 3052 patients consulting general practitioners for allergic rhinitis were studied. Patients were classified according to the 4 classes of ARIA. In all patients, quality of life (Rhinoconjunctivitis Quality-of-Life Questionnaire), sleep (Jenkins questionnaire), and work performance (Allergy-Specific Work Productivity and Activity Impairment questionnaire) were assessed.Results: Mild intermittent rhinitis was diagnosed in 11% of the patients, mild persistent rhinitis in 8%, moderate/severe intermittent rhinitis in 35%, and moderate/severe persistent rhinitis in 46%. The severity of rhinitis has more of an effect on quality of life, sleep, daily activities, and work performance than the duration of rhinitis. In moderate/severe rhinitis, more than 80% of patients report impaired activities, as opposed to only 40% with mild rhinitis.Conclusion: It seems that the term moderate/severe should be replaced by severe. A study in the general population is necessary, however, to assess the prevalence of the 4 ARIA classes of allergic rhinitis, especially in patients who are not consulting physicians for their symptoms.