Gene family evolution in green plants with emphasis on the origination and evolution of Arabidopsis thaliana genes
Gene family evolution in green plants with emphasis on the origination and evolution of Arabidopsis thaliana genes
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DOI：
10.1111/tpj.12089
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发表时间：
2013-03-01
期刊：
影响因子：
7.2
通讯作者：
Guo, Ya-Long
中科院分区：
文献类型：
--
作者：
Guo, Ya-Long
基因家族大小的变异是形成物种适应性自然变异的重要机制。尽管其重要性，基因家族大小的变化模式在绿色植物仍然没有得到很好的理解。特别是，基因和基因家族的进化模式仍然是未知的模式植物拟南芥的背景下，绿色植物。本研究以8种代表性的绿色植物基因组为样本，分别对拟南芥基因家族进化和拟南芥基因起源进行了研究。（2）某些基因家族的进化非常迅速，并伴随着极端的扩张或收缩，在所有8个物种中存在的2745个基因家族代表了绿色植物的核心蛋白质组;（iii）70%的拟南芥基因可以追溯到4.5亿年前;（iv）有趣的是，起源较早的拟南芥基因受到更强的纯化选择，也更保守。总之，本研究提供了全基因组的见解进化历史和机制的基因和基因家族的绿色植物，特别是拟南芥。
Gene family size variation is an important mechanism that shapes the natural variation for adaptation in various species. Despite its importance, the pattern of gene family size variation in green plants is still not well understood. In particular, the evolutionary pattern of genes and gene families remains unknown in the model plant Arabidopsis thaliana in the context of green plants. In this study, eight representative genomes of green plants are sampled to study gene family evolution and characterize the origination of A.thaliana genes, respectively. Four important insights gained are that: (i) the rate of gene gains and losses is about 0.001359 per gene every million years, similar to the rate in yeast, Drosophila, and mammals; (ii) some gene families evolved rapidly with extreme expansions or contractions, and 2745 gene families present in all the eight species represent the core' proteome of green plants; (iii) 70% of A.thaliana genes could be traced back to 450million years ago; and (iv) intriguingly, A.thaliana genes with early origination are under stronger purifying selection and more conserved. In summary, the present study provides genome-wide insights into evolutionary history and mechanisms of genes and gene families in green plants and especially in A.thaliana.