The contribution of a negative colorectal screening test result to symptom appraisal and help-seeking behaviour among patients subsequently diagnosed with an interval colorectal cancer.

The contribution of a negative colorectal screening test result to symptom appraisal and help-seeking behaviour among patients subsequently diagnosed with an interval colorectal cancer.
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DOI:
10.1111/hex.12672
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发表时间:
2018-08
期刊:
Health expectations : an international journal of public participation in health care and health policy
影响因子:
--
通讯作者:
Campbell C
Campbell C
中科院分区:
其他
文献类型:
--
作者:
Barnett KN;Weller D;Smith S;Steele RJ;Vedsted P;Orbell S;Moss SM;Melia JW;Patnick J;Campbell C

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使用愈创木粪潜血试验(GFOBt)的结直肠癌(CRC)筛查计划可降低结直肠癌死亡率。间歇性癌症在两轮筛查之间被诊断:来自阴性gFOBt的保证有可能影响间歇性结直肠癌的诊断途径。在苏格兰和英格兰进行了26次半结构化面对面访谈,这些人在gFOBt结果为阴性后被诊断为间歇性结直肠癌。参与者报告称,他们对gFOBt为负感到放心,并将他们的结果解读为“一切正常”。因此,大多数人并不怀疑癌症是导致症状的可能原因,许多人在症状评估期间也没有回忆起他们的筛查结果。在那些确实考虑过癌症,并确实考虑了他们的筛查测试结果的人中,gFOBt阴性让一些人感到放心,他们的症状的严重性被“淡化”了,一些受访者明确表示,他们的阴性测试结果导致他们推迟了寻求帮助的决定。筛查参与者需要被告知筛查的局限性和发生结直肠癌的持续风险,即使在收到阴性结果的情况下也是如此:应强调最大限度地减少对结直肠症状寻求医疗建议的延迟的重要性。
Colorectal cancer (CRC) screening programmes using a guaiac faecal occult blood test (gFOBt) reduce CRC mortality. Interval cancers are diagnosed between screening rounds: reassurance from a negative gFOBt has the potential to influence the pathway to diagnosis of an interval colorectal cancer. Twenty‐six semi‐structured face‐to‐face interviews were carried out in Scotland and England, with individuals diagnosed with an interval colorectal cancer following a negative gFOBt result. Participants reported they were reassured by a negative gFOBt, interpreting their result as an “all clear”. Therefore, most did not suspect cancer as a possible cause of symptoms and many did not recall their screening result during symptom appraisal. Among those who did consider cancer, and did think about their screening test result, reassurance from a negative gFOBt led some to “downplay” the seriousness of their symptoms with some interviewees explicitly stating that their negative test result contributed to a delayed decision to seek help. Screening participants need to be informed of the limitations of screening and the ongoing risk of developing colorectal cancer even when in receipt of a negative result: the importance of minimizing delay in seeking medical advice for colorectal symptoms should be emphasized.
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