Ontogeny of EEG-sleep from neonatal through infancy periods.
Ontogeny of EEG-sleep from neonatal through infancy periods.
复制标题
从新生儿到婴儿期脑电图睡眠的个体发育。
DOI：
10.1016/j.sleep.2007.08.014
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发表时间：
2008
期刊：
影响因子：
4.8
通讯作者：
Scher,MarkS
中科院分区：
文献类型：
--
作者：
Scher,MarkS
系列新生儿和婴儿脑电(EEG)-多导睡眠图研究记录了基于视觉检查或计算机分析的脑和非脑生理行为的个体发生。脑电模式及其与其他生理信号的关系作为正常大脑组织和成熟的模板，服从于多个相互连接的神经元网络。对连续脑电睡眠模式的解释也有助于跟踪从宫内到宫外的大脑功能的连续性。对行为和电信号模式个体发生的识别有助于洞察神经可塑性的发育神经生理学表达。新生儿和婴儿期的睡眠个体发育记录了出生后大脑成熟的预期模式，这允许在应激和/或病理条件下改变遗传编程的神经元过程。大脑和非大脑信号的自动分析提供了健康或疾病状态下大脑组织和成熟度的时间和频率相关的计算表型。与健康和疾病的发育起源有关的研究可以使用这些计算表型来设计纵向研究，以评估基因与环境的相互作用。计算策略可能最终提高我们的诊断技能，以识别特殊需要的儿童，并跟踪高危胎儿、新生儿和婴儿的神经康复护理。
Serial neonatal and infant electroencephalographic (EEG)–polysomnographic studies document the ontogeny of cerebral and noncerebral physiologic behaviors based on visual inspection or computer analyses. EEG patterns and their relationship to other physiologic signals serve as templates for normal brain organization and maturation, subserving multiple interconnected neuronal networks. Interpretation of serial EEG-sleep patterns also helps track the continuity of brain functions from intrauterine to extrauterine time periods. Recognition of the ontogeny of behavioral and electrographic patterns provides insight into the developmental neurophysiological expression of neural plasticity. Sleep ontogenesis from neonatal and infancy periods documents expected patterns of postnatal brain maturation, which allows for alterations from genetically programmed neuronal processes under stressful and/or pathological conditions. Automated analyses of cerebral and noncerebral signals provide time- and frequency-dependent computational phenotypes of brain organization and maturation in healthy or diseased states. Research pertaining to the developmental origins of health and disease can use these computational phenotypes to design longitudinal studies for the assessment of gene–environment interactions. Computational strategies may ultimately improve our diagnostic skills to identify special-needs children and to track the neurorehabilitative care of the high-risk fetus, neonate, and infant.